In recent times, public institutions rely on digital technologies; however, their effectiveness in achieving intended outcomes remains uncertain. The study aims to bridge this gap by investigating the nexus between e-Government practices and good governance in Ethiopian ministries, highlighting the mediating role of organizational agility. The data were collected using simple random sampling technique from 389 employees working in Ethiopian ministries. The descriptive statistics and the model fit were done via Jeffery’s amazing statistics program (JASP) while the proposed hypotheses were tested through partial least square structural equation modeling (PLS-SEM). The results confirm that e-Government practices exert a statistically significant positive effect on organizational agility and good governance. In turn, organizational agility significantly influences good governance. Furthermore, organizational agility explains 41.9% of the variance accounted for (VAF) on the direct paths, thereby signifies a complementary partial mediation role. The result underscores organizational agility functions as a vital conduit linking e-Government practices into good governance, underlining its role to the attainment of sustainable development goal 16. The novelty of the study stems from its integrative application of public value and dynamic capabilities theories, which broadens the empirical literature by providing deeper insights into e-government practices and organizational agility as co-evolving drivers of good governance. Moreover, policy makers and practitioners in Ethiopian ministries are expected to consider structural flexibility, mitigate administrative inertia, and proactively integrate emerging technologies to fully leverage the advantages engendered by e-Government practices.