471 results found

Ansley Unterberger, Alex Devarajan, Jack Zhang, Emery Monnig, Akhil Rao, Mehek Dedhia, George Wanna, Joshua Bederson, Raj Shrivastava

Background and Objectives: Vestibular schwannomas (VS) are slow-growing tumors of the vestibular nerve. Gross total resection (GTR) is recommended for large tumors (> 4cm), brainstem compression, cran...

Journal of Neuro-Oncology 2026-04-23 rs-9305641
Vestibular Schwannoma Adjuvant Radiotherapy Progression-Free Survival Residual Volume Tumor Burden

Shah Dhruv, Shubham Vaghasiya, Vivek Viroja

Deep learning models for automated knee osteoarthritis (OA) grading achieve high in-distribution accuracy but frequently exploit spurious image-acquisition cues — a phenomenon termed shortcut learning...

Research Square 2026-04-23 rs-9495057
shortcut learning knee osteoarthritis Kellgren–Lawrence grading gradient reversal layer domain generalization mutual information Integrated Gradients adversarial disentanglement

Ulka Vaishampayan, Jeremy (M. G.) Taylor, Deepak Kilari, Tanya Dorff, Alexandra Sokolava, Yaxuan Huang, Phillip Palmbos, Jacqueline Brown, Irene Tsung, Megan Caram, Sarah Yentz, Bassel Nazha, Zachery Reichert, Joshi Alumkal

Background: Effective therapies remain a currently unmet need for neuroendocrine prostate cancer (NEPC). Preclinical synergy in small cell cancer, and clinical tolerability led to the conduct of a mul...

Nature Portfolio 2026-04-23 rs-9471666
immune checkpoint therapy anti-vascular therapy small cell prostate cancer

Alon Gorenshtein, Mahmud Omar, Yiftach Barash, Jonathan B. Kruskal, Muneeb Ahmed, Olga R. Brook, Ben Illigens, Girish N. Nadkarni, Eyal Klang

Large language models are increasingly used in clinical medicine, but their reliance on cloud servers conflicts with patient-privacy requirements and excludes resource-limited healthcare systems. Smal...

Research Square 2026-04-23 rs-9488729
Small Language Models Agentic AI Large Language Models Systematic Review Clinical Natural Language Processing Edge Deployment PRISMA

Zhaoxue Ci, Weijia Zhang

Variations in family size may significantly shape the adoption of preventive health behaviors, particularly among aging populations. Using data from the 2021 Chinese General Social Survey (CGSS), this...

Research Square 2026-04-23 rs-9298848
Older Adults Children number Vaccination Preventive Health Behavior

Farhana Haque, Rumana Islam

Moyamoya disease is a rare, progressive cerebrovascular disorder characterized by stenosis or occlusion of the terminal internal carotid arteries and the formation of abnormal collateral vessels at th...

Research Square 2026-04-23 rs-9446926
suzuki staging seizure moyamoya disease magnetic resonance angiography dysphagia cerebral ischemia

Peng Li, Zhiyong Zhu, Hon Ki Tsang, Yi Wang, Sheng Wang, Haoyu Zhang, Hui Wang, Dehui Li, Chenchen Ma, Jiashu Wang, Rui You

Near-infrared (NIR) photodetectors are critical for numerous applications including optical communications, biomedical imaging, and night vision. However, conventional photodetectors suffer from an in...

Nature Portfolio 2026-04-23 rs-9480794
photodetector infrared PtSe2 photoresponsivity response speed flexible extreme temperature

Xi Chen, Zexu Wei, Ranran Yu, junnan Xu, Chenyu Tao, Aixia Zhang, Longjie Li, Xiaoshan Zhang, Jin He, Jiajun Yu, Xuhuang Xiao, Jiahui Guo, Tong Wang, Wei Gong, Yanbo Wang, Chen-Yu Zhang, Dijun Chen, Zhang-Peng Chen, Chenbo Ji

Postnatal depression (PND) increases the risk of neurodevelopmental impairments in offspring, yet the underlying mechanisms remain elusive. Here, we identify an intergenerational signaling pathway thr...

Research Square 2026-04-23 rs-9008493

Arman Ghavidel, Pilar Pazos, Hyoshin J. Park, John Seems

Prostate cancer risk prediction remains challenged by the inability to reliably distinguish indolent from aggressive disease, leading to overtreatment or undertreatment. Conventional approaches based ...

Research Square 2026-04-23 rs-9490581
Prostate cancer Risk stratification Longitudinal PSA/DRE Deep learning Outcome-guided clustering

Sara Pires, Lapo Mughini-Gras, Sandra Hoffmann, Kunihiro Kubota, Shannon Majowicz, Martyn Kirk, Lucy Robertson, Paul Torgerson, Lea Jakobsen, Antonio Agudo, Li Bai, Tety Rachmawati, Yuki Minato, Charlee Roberts, Arie Havelaar, Brecht Devleesschauwer, Elisa Benincà, Robin Lake, Tine Hald, Roger Cooke, Willy Aspinall, Gabriela Nane

Identifying the sources of foodborne diseases is crucial for guiding national food safety strategies and supporting policies that promote safe and sustainable diets. We present global estimates of the...

Research Square 2026-04-23 rs-9449162
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