497 results found

Zheng Yanqing, Tang Xike, Pang Xiaofeng, Fang Yinmei, Mo Lida, Luo Xiaolu, Xiao Manqi

Talaromyces marneffei (T. marneffei) is a life-threatening dimorphic fungus endemic to southern China and Southeast Asia, with triazole resistance emerging as a critical clinical challenge in immunoco...

Scientific Reports 2026-04-22 rs-9153081
Talaromyces marneffei triazole resistance Erg3 gene antifungal susceptibility

Xinyu Wang, Chenyu Zhang, Hui Xue, Xuequn Cheng, Chao Liu, Xiaogang Li

This work reveals a stage-dependent reversal of corrosion susceptibility between CGHAZ and FGHAZ of welded 650 MPa high-strength low-alloy steel under wet–dry cyclic in 0.01 mol/L NaHSO3. In the initi...

npj Materials Degradation 2026-04-22 rs-9375005
Sulfite-containing environment Grain Size Rust layer evolution Corrosion resistance Machine learning

Yashwanth Sanka

Decentralized Web Applications (dApps) built on blockchain, Web3 technologies, and the Inter- Planetary File System (IPFS) are emerging as a promising solution to longstanding challenges in agricultur...

Research Square 2026-04-22 rs-9450706
Agriculture Blockchain Decentralized Applications (dApps) Internet of Things (IoT) Smart Contracts Supply Chain Traceability Systematic Review Web3

Mads Gyrd-Hansen, John Rizk, Frederik Timmermann, Wenxin Lyu, Kit Lee, Majken Kjær, Miriam Beichler, Berthe Fiil, Malin Jessen, Giulia Franciosa, Jesper Olsen, Max Sauerland, Rune Damgaard, Dominik Priesmann

Met1-linked ubiquitin (Met1-Ub) assembled by LUBAC crucially regulates immune receptor signalling. However, the regulation of LUBAC’s function remains widely debated. Here, we reveal that the interact...

Nature Portfolio 2026-04-22 rs-5519483
LUBAC PUB domain Met1-linked ubiquitin OTULIN CYLD SPATA2 TNF immune receptor inflammation cell death immunology

Longcheng Luo, Xiaofan Zhang, Shun Yang, Qihang Huang, Kai Xiao, Cunfu Wang

The paper proposes a partition-based topology optimization approach for multi-axis additive manufacturing(AM), aiming to fully leverage its advantages in dynamic build orientation adjustment and regio...

Engineering with Computers 2026-04-22 rs-9018541
Multi-axis additive manufacturing Topology optimization Voronoi diagram based decomposition Overhang control Build orientation optimization

Riham Hilal, Mona G Ibrahim

AI technology development has transformed the field of engineering education with its adaptivity-driven, data-based, and ethical-led learning platforms that promote equity, diversity, and inclusivity....

Research Square 2026-04-22 rs-9458060
Artificial Intelligence (AI) Engineering Education Equality Diversity Inclusion (EDI) Ethical Leadership Human-Centered Learning Adaptive Pedagogy Digital Transformation Bias Mitigation Accessibility in STEM Sustainable Development Goals (SDGs); Gender Equality (SDG 5); Reduced Inequalities (SDG 10)

Shubham Kumar, Nihar Kumar Mahato, Md Abu T Ansary, Debdas Ghosh

Uncertain multiobjective optimization problems arise in various real-world scenarios where ob-jectives are affected by uncertainty. To address this, we propose a quasi-Newton method to solve the robus...

Soft Computing 2026-04-22 rs-9344639
Multiobjective optimization problem Uncertainty Robust optimization Robust efficiency Quasi Newton's method Line search techniques.

Zixing Xu, Zhechen Li, Xinhao Huang, Chuanrong Chen, Changyi Jiang, Weihong Xu

Spinal cord injury (SCI) often leads to significant neurological impairment and poses a substantial therapeutic challenge, with disulfidptosis recently identified as a potential mechanism exacerbating...

Molecular Neurobiology 2026-04-22 rs-9253233
Spinal cord injury Bisphenol A Disulfidptosis Metabolomics Key genes Key metabolites

Mustofa Ali Said

The strength prediction of adhesive-bonded single lap joints (SLJs) is essential for reliable joint design. However, due to the non-linear interactions between geometrical parameters and material prop...

Research Square 2026-04-22 rs-9478810
Adhesive bonding Single lap joint GFRP composites Taguchi method MLR ANN Failure load prediction

Eshal Atif, Mazhar Ali, Mohib Ali Hassan, Vishan Das, Fnu Urooba, Abdal Ahmed, Muhammad Mukhlis, Mannal Ahmed, Daniyal Ahmed, Mohammad Dawar Zahid, Sadia Qazi, Muhammad Atif Mazhar

Background:Dementia is a leading cause of death in older adults in the United States, and the population at greatest risk is expanding as post-war birth cohorts move through later life. Existing natio...

Research Square 2026-04-22 rs-9474865
Dementia mortality forecasting health inequalities long-term care end-of-life care CDC WONDER older adults
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