SinoXivBackground: Anxiety disorders, depression, and borderline personality disorder often emerge during adolescence, yet early psychiatric assessment remains challenging because conventional interviews are...
Organ-specific aging measures have recently gained growing attention. Still, the interpretation of the contributing factors, biological mechanism and relevance of the physiological insights remain unc...
Met1-linked ubiquitin (Met1-Ub) assembled by LUBAC crucially regulates immune receptor signalling. However, the regulation of LUBAC’s function remains widely debated. Here, we reveal that the interact...
A pipeline for improved 16S rRNA gene-based phylogeny and diversity analyses of Bacteria and Archaea
The LTP database compiling 16S rRNA gene sequences of all type strains of Bacteria and Archaea has served taxonomists for two decades. Here we report the LTPlus, a manually curated and aligned databas...
The solar photosphere contains a huge amount of small-scale magnetic flux. However, this small-scale flux remains unresolved due to observational limitations. We investigated the net magnetic flux bel...
As mental health disorders continue to rise globally and access to specialised care remains a persistent challenge, AI-powered conversational agents have emerged as a credible avenue for early screeni...
Large language models require high-quality human feedback for alignment and fine-tuning, yet platforms face the fundamental challenge of incentivizing valuable contributions while screening out potent...
Background Economic crises threaten the sustainability of universal health coverage (UHC), particularly in low- and middle-income countries where preventive health systems operate with constrained res...
Background Explosive power is a key determinant of soccer performance and is closely associated with lower extremity joint function, particularly hip and knee range of motion (ROM) and muscle strength...
Global semiconductor shortages beginning in 2020, combined with geopolitical supply disruptions extending through 2025, imposed material constraints on hyperscale cloud infrastructure expansion that c...
