216 results found

Ihoghosa Iyamu, Devon Haag, Sofia Bartlett, Catherine Worthington, Daniel Grace, Mark Gilbert

Background Digital interventions designed to expand access to sexually transmitted and blood-borne infection (STBBI) testing are promoted to advance equitable health services. Yet many remain pilot pr...

Implementation Science Communications 2026-04-21 rs-9227568
Digital Health Sustainability Implementation Science Health systems STBBIs

Yanjun Huang, Jia Li, Haowei Chen, Tianyu Chen, Wenhao Liu, Guangfeng Ruan, Jun Liu, Zhong Alan Li, Ying Tang, Li Jiang, Changhai Ding, Jing Liao, Xiaoshuai Wang

Background Sarcopenia is a global challenge and a potential modifiable risk factor for cardiorenal diseases. However, the geospatial variation of sarcopenia in China and its region-specific associatio...

BMC Public Health 2026-04-21 rs-9213148
Sarcopenia Geospatial analysis CHARLS cardiovascular disease (CVD) chronic kidney disease (CKD)

Simona Pagliuca, Vincent Alcazer, Mélanie Gaudfrin, Nicole Raus, Anne Huynh, Raynier Devillier, Arda Dumaz, Ashwin Kishtagari, Lukasz Gondek, Mark Juckett, Suresh Kumar Balasubramanian, Marie Robin, Ibrahim Yakoub-Agha, Edouard Forcade, Claude Eric Bulabois, Jean-Baptiste Méar, Patrice Chevallier, Cristina Castilla Llorente, Xavier Poiré, Michaël Loschi, Johan Maertens, Stéphanie Nguyen, Frédéric Baron, Etienne Daguindau, Natacha Maillard, Florent Malard, Alice Aarnink, Maud D’Aveni-Piney, Marie Thérèse Rubio, Francesca Ferraro, Valeria Visconte, Tobias Lenz, Carmelo Gurnari, Jaroslaw Maciejewski

Allogeneic hematopoietic cell transplantation (allo-HCT) remains the only curative option for many hematologic malignancies, yet transplant-related toxicity and relapse continue to constrain long-term...

Research Square 2026-04-21 rs-9383323

Benjamin J. M. Gooddy, Laila Rida, Bryony Goulding Mew, Ana Rita Moura, Timea Szentgyorgyi, Brandi Eiff, Luisa Schalk, Iman Rafiq, Cathy Davies, Daniel Martins, Lilla A Porffy, Christabel Gibson, Caroline Wooldridge, Giorgio Bergamini, Janet R Nicholson, Markus Waser, Elizabeth Tunbridge, Sigurd D Süssmuth, Valdemar Robert Janulczyk, Karla V Allebrandt, Adam Hampshire, Sukhwinder S. Shergill, Steve Williams

Background Slow participant recruitment is one of the predominant determinants of failure or delay across clinical research. Even when recruitment targets are met, study populations may be unrepresent...

BMC Psychiatry 2026-04-21 rs-9292013
Participant Recruitment Depression Psychosis Schizophrenia Psychiatry Psychiatric Research Major Depressive Disorder Clinical Study Digital Health Clinical Research

Sara Damiani, Priscilla Guglielmo, Guya Mansi, Sara Calzolai Lettieri, Giulia Giacoppo, Demetrio Aricò, Lucia Setti, Alessia Artesani, Giovanni Lughezzani, Angelo Porreca, Antonio Selvaggio, Laura Evangelista

Objective. Radiolabelled PSMA PET/CT has demonstrated high diagnostic accuracy in staging patients with intermediate-risk prostate cancer (PCa). However, its role on long-term prognosis and outcome pr...

Annals of Nuclear Medicine 2026-04-21 rs-9347158
prostate cancer intermediate-risk PSMA PET prognosis

Tânia R. Dias, Beatriz Almeida, Pedro Cruz, Mário Sousa Pimenta, Manuel Morais, Luís Rocha, Jose Manuel Martinez, Ana Luísa Teixeira, Júlio Oliveira, Francisca Dias, Rui Medeiros

Cancer patients are at increased risk of severe COVID-19 outcomes. Understanding their immunological response to SARS-CoV-2 mRNA vaccination is essential for identifying molecular biomarkers that can ...

Scientific Reports 2026-04-21 rs-9169442
COVID-19 Vaccine miRNAs Cancer Biomarkers

Aleksander Stupnicki, Bernardo Mendes, Maxwell Reinstein, Ariel Ong, Andrew Malem, Pearse Keane, Arun Thirunavukarasu

Background Generative artificial intelligence (genAI) chatbots are increasingly used for health advice despite lacking regulatory approval, raising concerns about their output quality and safety. This...

Research Square 2026-04-21 rs-9383173

Luís Jesuíno de Oliveira Andrade, Gabriela Correia Matos de Oliveira, Alcina Maria Vinhaes Bittencourt, Osmário Jorge de Mattos Salles, Luís Matos de Oliveira

Introduction: Obesity is associated with measurably attenuated postprandial incretin responses, characterized by blunted glucagon-like peptide-1 (GLP-1) secretion and functional resistance to glucose-...

Research Square 2026-04-21 rs-9453154
Enteroendocrine dysfunction GLP-1 secretion Incretin resistance Metabolic maladaptation

Mostafa Hegy, Amira M. El Nazer, Adnene Laf, Efrem Amanuel Data

This study presents a forecasting and comparative analysis of moderate geomagnetic storms using artificial neural networks (ANNs). Four moderate geomagnetic storm events that occurred during 2022, in ...

Research Square 2026-04-21 rs-9461478
Geomagnetic storms SYM-H index Coronal mass ejections Artificial neural networks Space weather forecasting

Arnim Kargl, Henrik Ebel, Peter Eberhard

Multibody dynamics research has enabled efficient and effective simulation, design optimization, control, and identification of mechanical systems, contributing significantly to applications as divers...

Research Square 2026-04-21 rs-9439249
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