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Open Access Academic Papers from Research Square

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Research Article under-review

Long-Term Culture of Bone Marrow Mesenchymal Stromal Cells Produces Distinct Populations of Extracellular Vesicles While Preserving Their Core Functionalities and Integrities

Doste R. Mamand, Lovisa Bli, Felix Sandberg, Mariana Castañeda Mesa, Osama Saher, Ilamathi Hema S aranya, André Görgens, Oscar P.B Wiklander

Efficient and reproducible production of mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) is essential for their therapeutic application. In this study, we investigated, for the first...

Journal of Nanobiotechnology 2026-04-21 rs-9376497
EVs BMMSCs serum-free media Tetraspanins size morphology zeta potential proliferation migration immunomodulation
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