Background Adverse Event Reporting Systems (AERS) are essential tools for improving patient safety, yet under-reporting by medical staff remains a persistent challenge. Existing studies mainly adopt v...
Phase II trial of Pembrolizumab and Lenvatinib in Advanced Neuroendocrine Prostate Cancer (PLANE-PC)
Background: Effective therapies remain a currently unmet need for neuroendocrine prostate cancer (NEPC). Preclinical synergy in small cell cancer, and clinical tolerability led to the conduct of a mul...
Prostate cancer risk prediction remains challenged by the inability to reliably distinguish indolent from aggressive disease, leading to overtreatment or undertreatment. Conventional approaches based ...
Identifying the sources of foodborne diseases is crucial for guiding national food safety strategies and supporting policies that promote safe and sustainable diets. We present global estimates of the...
This study investigated regional variations in hospitalization expenses for lung malignant tumor patients within tertiary hospitals. Using H City as the reference point and comparing it with B, M, and...
This in-depth investigation employs network pharmacology and molecular docking methodologies to analyse various phytocompounds extracted from the hamamelis plant, with a specific focus on uncovering p...
Background Incorporating immunotherapy effectively remains a priority in therapeutic research of ovarian cancer, making it essential to conduct and report randomized, controlled trials (RCTs) with hig...
Background Transurethral resection of bladder tumor (TURBT) is the standard treatment for non-muscle-invasive bladder cancer (NMIBC), but the high rates of residual tumor and recurrence remain major c...
Background Rituximab based chemotherapy regimens, particularly R-CHOP, are highly effective for the treatment of B-cell lymphoma (BCL) but are frequently complicated by pulmonary adverse effects (PAEs...
Purpose The neutrophil-to-lymphocyte ratio (NLR) is an emerging biomarker for predicting febrile neutropenia (FN) in cancer patients. This study aimed to evaluate the association between pre-treatment...
SinoXiv