Paper List

William Foulkes, Kenzie Melvill, Leora Witkowski, Céline Domecq, Nancy Hamel, Justin Mayers, Sofia Maia, Manuel Teixeira, Inês Francisco, Cristina Albuquerque, Olivia Tan, Kevin McDonnell, Alexandra Capasso, George Chong, Victoria Marcus, Carla Pinto

In certain populations, founder pathogenic variants are a common cause of Lynch syndrome. Here, we report the identification of a novel founder variant, NM_000179.3 (MSH6):c.2061T > G (p.Cys687Trp). O...

Yanchu Tong, Wenkui Chen, Shun Deng, Lu Qin

Objective: To investigate the role of DISP3 in thyroid cancer (TC) progression and its modulation of the tumor immune microenvironment. Methods: Bioinformatics analyzed DISP3 expression and its progno...

Riya Albert, Joshua Thomas, Navid Sadeghi, Sangeetha Reddy, Glenda Delgado, Heather McArthur, Samira Syed, Deborah Farr, Nisha Unni

Introduction Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by poor prognosis. Based on the KEYNOTE-522 trial, neoadjuvant pembrolizumab plus chemotherapy has become the s...

Yanxue Lian, Grace Kenny, Karen Peacock, Sonya Chew, Elaine Grehan, Kerin Michael, Ananya Gupta

Aim: This pilot study explored the feasibility and preliminary effects of a home-based complex exercise programme compared with Pilates in breast cancer survivors with lymphoedema, delivered and asses...

Jiayi Zhao, Yao Tong, Yunchao Huang, Chao Zhang, Hongjiang Zhang, Zhenghong Yang, Fang Li, Yang Luo, Dinglin Zhang

Background The incidence and mortality rates of lung cancer (LC) are extremely high and continue to rise. Early diagnosis combined with timely intervention can effectively reduce mortality in LC patie...

Pitithat Puranachot, Thivaratana Sinthuwiwat, Priyavudh Herabutya, Kanthida Jangyubol, Bongkod Petcharat, Jutamas Yimnoon, Jitsopin Phadungsut, Chayanee Samdaengpan, Chumut Phanthunane

Background: Accurately predicting treatment outcomes in patients with advanced non-small cell lung cancer (NSCLC) remains a significant clinical challenge. While circulating tumor DNA (ctDNA) within p...

Tan Haosheng, Yu Dapeng, Jiao lianghe

Background Tumor epithelial barriers physically impede immune cell infiltration, causing immune exclusion and resistance to immune checkpoint inhibitors (ICIs). However, a simple, spatially quantifiab...

Jun Yu, Jie Huang, Qinghua Ma, Yanyu Chen, Xinyue Huang, Jian Chen

Background: Sarcopenia represents a highly prevalent and prognostically detrimental complication in patients with bone tumors. Its progressive and dynamic nature hinders early intervention and amplifi...

Yan Ding, Juan Yu, Min Liu, Xiangyu Liu, Ling Kang, Liujing Huang, Jinze Li, Yanan Wang, Xin Xu, Min Zhao, Ping Wei, Shuangbiao Li, Zaibo Li, Yueping Liu

Background Neoadjuvant therapy (NAT) is crucial for locally advanced breast cancer, but post-NAT lymph node assessment is challenging due to histological changes. Current methods like immunohistochemi...

jingrong Wang, Yujuan Peng, Rui Fan, Jian Hu, Tong Chen, Wen Shi

Objective: This study aimed to develop and evaluate a multi-stage optimisation strategy based on the thirst management model to alleviate perioperative thirst and dry mouth symptoms in patients with g...