6 results found

Alon Gorenshtein, Mahmud Omar, Yiftach Barash, Jonathan B. Kruskal, Muneeb Ahmed, Olga R. Brook, Ben Illigens, Girish N. Nadkarni, Eyal Klang

Large language models are increasingly used in clinical medicine, but their reliance on cloud servers conflicts with patient-privacy requirements and excludes resource-limited healthcare systems. Smal...

Research Square 2026-04-23 rs-9488729
Small Language Models Agentic AI Large Language Models Systematic Review Clinical Natural Language Processing Edge Deployment PRISMA

Kathryn R. Macapagal, Krystal L. Madkins, Ashley Knapp, Manuel Hurtado, Jr., Mariajosé Paton, Bryant Norton, Josephine Owusu, Isaac Greenawalt, Dennis H. Li, Brian Mustanski

Background Digital HIV prevention interventions (DHIs) are efficacious in increasing prevention behaviors, and delivering them direct-to-consumer (DTC) expands their reach. However, few have successfu...

Implementation Science Communications 2026-04-23 rs-9202620
Digital health interventions Direct-to-consumer (DTC) interventions hybrid effectiveness-implementation study HIV prevention

Robert Topp, Jay Greenstein, Jena Etnoyer-Slaski

Background Musculoskeletal disorders (MSDs) are the leading cause of disability worldwide and the primary reason for healthcare utilization. Understanding a patient's rehabilitation goals and their mo...

Chiropractic & Manual Therapies 2026-04-23 rs-9346912
Health Status Patient Adherence Mobile Applications Healthcare Costs Patient Retention Digital Health Remote Therapeutic Monitoring (RTM) Chiropractic Behavioral Science

Ihoghosa Iyamu, Devon Haag, Sofia Bartlett, Catherine Worthington, Daniel Grace, Mark Gilbert

Background Digital interventions designed to expand access to sexually transmitted and blood-borne infection (STBBI) testing are promoted to advance equitable health services. Yet many remain pilot pr...

Implementation Science Communications 2026-04-21 rs-9227568
Digital Health Sustainability Implementation Science Health systems STBBIs

Benjamin J. M. Gooddy, Laila Rida, Bryony Goulding Mew, Ana Rita Moura, Timea Szentgyorgyi, Brandi Eiff, Luisa Schalk, Iman Rafiq, Cathy Davies, Daniel Martins, Lilla A Porffy, Christabel Gibson, Caroline Wooldridge, Giorgio Bergamini, Janet R Nicholson, Markus Waser, Elizabeth Tunbridge, Sigurd D Süssmuth, Valdemar Robert Janulczyk, Karla V Allebrandt, Adam Hampshire, Sukhwinder S. Shergill, Steve Williams

Background Slow participant recruitment is one of the predominant determinants of failure or delay across clinical research. Even when recruitment targets are met, study populations may be unrepresent...

BMC Psychiatry 2026-04-21 rs-9292013
Participant Recruitment Depression Psychosis Schizophrenia Psychiatry Psychiatric Research Major Depressive Disorder Clinical Study Digital Health Clinical Research

Sara Alferjani, Mohamed HADi Mohamed Abdelhamid, Amal Benkorah

Background: Antiretroviral stock-outs in conflict-affected regions like Libya disrupt essential HIV treatment, risking viral suppression and health outcomes. However, the specific clinical impact of t...

Research Square 2026-04-21 rs-9451632
HIV antiretroviral stock-outs viral load suppression adherence co-infection digital health Libya
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