2 results found

Neziha Senem Arı, Ayşe Çakır Gündoğdu, Neslihan Meriç, Orhan Özatik

Background Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed in oncology settings, yet their direct effects on endometrial cancer cell fate and survival signaling remain unclear....

Medical Oncology 2026-04-22 rs-8850312
Fluoxetine Endometrial cancer ERK1/2 signaling Phosphorylated ERK1/2 (pERK1/2) Annexin V/propidium iodide TUNEL assay

William Foulkes, Kenzie Melvill, Leora Witkowski, Céline Domecq, Nancy Hamel, Justin Mayers, Sofia Maia, Manuel Teixeira, Inês Francisco, Cristina Albuquerque, Olivia Tan, Kevin McDonnell, Alexandra Capasso, George Chong, Victoria Marcus, Carla Pinto

In certain populations, founder pathogenic variants are a common cause of Lynch syndrome. Here, we report the identification of a novel founder variant, NM_000179.3 (MSH6):c.2061T > G (p.Cys687Trp). O...

European Journal of Human Genetics 2026-04-21 rs-9172566
Founder variant Lynch syndrome variant of uncertain significance immunohistochemistry haplotype endometrial cancer
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