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Open Access Academic Papers from Research Square

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Article under-review

ATF6 shapes PERK and IRE1 signaling dynamics during ER stress

Susan Logue, Gideon Ong, Masozi Palata, Suraj Shaji, Joel Pearson

The Unfolded Protein Response (UPR) is a conserved network of signaling pathways controlled by the Endoplasmic Reticulum (ER) anchored stress sensors IRE1, PERK and ATF6. The UPR’s primary function is...

Cell Death & Disease 2026-04-21 rs-9373070
Endoplasmic Reticulum Stress Unfolded Protein Response ATF6 IRE1
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