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results found
Background: To curb the emergence of antibiotic-resistant Mycobacterium leprae strains, the WHO recommends monitoring of antimicrobial resistance (AMR). In Madagascar, molecular surveillance of resist...
Mycobacterium leprae
Madagascar
RLEP qPCR
Drug resistance
Genotype
1D-Malagasy
anti-PGL-I serology
Background: Mutations in intermediate filament genes cause over 100 human diseases, yet predicting clinical severity from genotype remains unreliable due to phenotypic variability and the prevalence o...
intermediate filament
FoldX
ΔΔG
variant interpretation
genotype–phenotype correlation
protein stability
SinoXiv