SinoXivPurpose To develop and verify a physiologically based pharmacokinetic (PBPK) modeling strategy for mithramycin (MTM) and its analog, MTMSA-Trp, with the aim of projecting first-in-human plasma pharmac...
Pharmaceutical contaminants, such as Cefuroxime sodium, pose a significant threat to aquatic ecosystems due to their persistence and bioactivity. This study reports the synthesis of sustainable mesopo...
Background Oral administration is the preferred route for drug delivery due to convenience and patient compliance, yet its efficacy is hampered by low solubility and enzymatic degradation. Nanoparticu...
To address the challenge of textile waste upcycling, this study demonstrates a sustainable, acid-assisted hydrothermal strategy to transform waste cotton fibers into high-value functional carbon mater...
Traditional approaches to anticancer dosing typically rely on fixed protocols that often overlook how patients respond differently to treatment. This can limit both effectiveness and safety. In this w...
Background This research sheds light on one of the contaminants of the emerging concern, oxytetracycline (OTC), a commonly used antibiotic used to treat infections and diseases caused by bacteria. Num...
