SinoXivUmbilical cord blood (UCB) transplantation effectively treats pediatric hematologic disorders, but insufficient multipotent progenitors delay immune reconstitution, severely restricting its clinical a...
Background Bladder cancer (BC) is a common urologic malignancy with high recurrence and progression rates, and outcomes for advanced disease remain poor. Peroxisome proliferator-activated receptor gam...
Spinal cord injury (SCI) often leads to significant neurological impairment and poses a substantial therapeutic challenge, with disulfidptosis recently identified as a potential mechanism exacerbating...
Ginkgolide B (GB), a diterpenoid lactone compound derived from Ginkgo biloba extract, exhibits anti-inflammatory and inhibits neuroexcitotoxicity. However, its specific pharmacological effects and mec...
Alzheimer’s disease is a progressive neurodegenerative disorder characterized by cognitive decline and widespread cellular dysfunction. While individual pathological features such as mitochondrial imp...
Chronic exposure to high-altitude hypoxia impairs hippocampus-dependent learning and memory. However, the upstream mitochondrial mechanisms by which oxygen deficiency triggers synaptic dysfunction rem...
