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Open Access Academic Papers from Research Square

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Research Article under-review

A Lactylation-Related Radiosensitivity Index Predicts Differential Radiotherapy Benefit in Head and Neck Squamous Cell Carcinoma

Wang Zhe, Xiong Yan

Radiotherapy (RT) is integral to the management of head and neck squamous cell carcinoma (HNSCC), yet no validated biomarker exists to predict which patients benefit most. Lactylation, a metabolic pos...

Discover Oncology 2026-04-21 rs-9250884
Head and neck squamous cell carcinoma Lactylation Radiosensitivity Predictive biomarker Tumor immune microenvironment
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