76 results found

Jian Ding, Yixiao Zhou

This paper develops a unified framework that extends the Alchian–Allen mechanism beyond the restrictive assumption of close substitutes. The framework emphasizes a fixed-cost selection mechanism in wh...

Review of World Economics 2026-04-22 rs-9331302

Miguel Brieno-Enriquez, Maria López-Panadés1, Ana Martinez-Marchal, Esther Choi, Andrew Levy, Tianjiao Chu, Shruthi Shivkumar, Justin Bochter, Juan Morales, Patrick Walsh, Marta Martin-Ruiz, Gretchen Rosado, Jimmaline Hardy, Yang Hu, Jiefei Wang, Cristina Madrid-Sandín, Andros Maldonado-Linares, Lidia Yang, Èlia Ramos-Ramells, Lisa Barton, Eric Duval, Edana Stroberg, Sanjay Mukhopadhyay, Uma R Chandran, Amanda Colvin Zielen, Kyle Orwig, Olivier Elemento, Carmen Marquez, Subha Ghosh, Lluis Bassas, Guilherme Costa, Ignasi Roig

SARS-CoV-2 coronavirus emerged in 2019, leading to the Coronavirus disease 2019 (COVID-19). Expression of viral entry factors such as ACE2 and TMPRSS2 is higher in the testis, particularly in Sertoli ...

Research Square 2026-04-21 rs-9371895
COVID-19 Spermatogonial stem cell Sertoli cell human testis snRNAseq brain

Yanjun Huang, Jia Li, Haowei Chen, Tianyu Chen, Wenhao Liu, Guangfeng Ruan, Jun Liu, Zhong Alan Li, Ying Tang, Li Jiang, Changhai Ding, Jing Liao, Xiaoshuai Wang

Background Sarcopenia is a global challenge and a potential modifiable risk factor for cardiorenal diseases. However, the geospatial variation of sarcopenia in China and its region-specific associatio...

BMC Public Health 2026-04-21 rs-9213148
Sarcopenia Geospatial analysis CHARLS cardiovascular disease (CVD) chronic kidney disease (CKD)

Simona Pagliuca, Vincent Alcazer, Mélanie Gaudfrin, Nicole Raus, Anne Huynh, Raynier Devillier, Arda Dumaz, Ashwin Kishtagari, Lukasz Gondek, Mark Juckett, Suresh Kumar Balasubramanian, Marie Robin, Ibrahim Yakoub-Agha, Edouard Forcade, Claude Eric Bulabois, Jean-Baptiste Méar, Patrice Chevallier, Cristina Castilla Llorente, Xavier Poiré, Michaël Loschi, Johan Maertens, Stéphanie Nguyen, Frédéric Baron, Etienne Daguindau, Natacha Maillard, Florent Malard, Alice Aarnink, Maud D’Aveni-Piney, Marie Thérèse Rubio, Francesca Ferraro, Valeria Visconte, Tobias Lenz, Carmelo Gurnari, Jaroslaw Maciejewski

Allogeneic hematopoietic cell transplantation (allo-HCT) remains the only curative option for many hematologic malignancies, yet transplant-related toxicity and relapse continue to constrain long-term...

Research Square 2026-04-21 rs-9383323

Nobuyuki Akutsu, Hideya Hayashi, Nao Tachizawa, Junji Koyama, Atsufumi Kawamura, Takashi Sasayama

Although acute subdural hematoma (ASDH) and extensive retinal hemorrhage (RH) in infants are widely regarded as characteristic findings of abusive head trauma (AHT), they have also been reported in as...

Research Square 2026-04-21 rs-9071916
abusive head trauma subdural hematoma retinal hemorrhage shaken baby syndrome short-distance falls

Benjamin J. M. Gooddy, Laila Rida, Bryony Goulding Mew, Ana Rita Moura, Timea Szentgyorgyi, Brandi Eiff, Luisa Schalk, Iman Rafiq, Cathy Davies, Daniel Martins, Lilla A Porffy, Christabel Gibson, Caroline Wooldridge, Giorgio Bergamini, Janet R Nicholson, Markus Waser, Elizabeth Tunbridge, Sigurd D Süssmuth, Valdemar Robert Janulczyk, Karla V Allebrandt, Adam Hampshire, Sukhwinder S. Shergill, Steve Williams

Background Slow participant recruitment is one of the predominant determinants of failure or delay across clinical research. Even when recruitment targets are met, study populations may be unrepresent...

BMC Psychiatry 2026-04-21 rs-9292013
Participant Recruitment Depression Psychosis Schizophrenia Psychiatry Psychiatric Research Major Depressive Disorder Clinical Study Digital Health Clinical Research

Luís Jesuíno de Oliveira Andrade, Gabriela Correia Matos de Oliveira, Alcina Maria Vinhaes Bittencourt, Osmário Jorge de Mattos Salles, Luís Matos de Oliveira

Introduction: Obesity is associated with measurably attenuated postprandial incretin responses, characterized by blunted glucagon-like peptide-1 (GLP-1) secretion and functional resistance to glucose-...

Research Square 2026-04-21 rs-9453154
Enteroendocrine dysfunction GLP-1 secretion Incretin resistance Metabolic maladaptation

Morsi Abdalla Shaban

This study proposes an applied multi-criteria decision-making framework for prioritizing school reconstruction in post-conflict environments under epistemic uncertainty. The framework synthesizes poli...

Research Square 2026-04-21 rs-9461290
MCDM Fuzzy AHP Entropy TOPSIS Dirichlet Distribution Rank Stability School Reconstruction Gaza Strip

Li Ranfei, Wang Sirui, Yang Qiying

CRISPR-Cas9 screening enables systematic identification of gene dependencies across diverse cancer cell lines. However, distinguishing lineage-specific vulnerabilities from broadly essential genes rem...

Research Square 2026-04-21 rs-9463556
CRISPR-Cas9 DepMap cancer dependency bioinformatics lineage-specific targets nucleotide metabolism

Yue Zhang, Liangxu Xu, Guilin Chen, Hongjun Liu, Xuan Zhao, Chao Yao, Haonan Si, Mao Lin, Yu Wang, Bingwu Wang, Xiangjie Yin, Jing Yuan, Guixing Qiu, Zhihong Wu, Terry Zhang, Xiaojuan Ban, Qingliang Liao, Nan Wu

Early identification of scoliosis is highly significant for timely intervention and efficient management of the disease. However, conventional static screening approaches rely heavily on subjective as...

Nature Portfolio 2026-04-21 rs-9438984
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