76 results found

Serhat Atalar, Gürdal Yılmaz, Ahmet Eroğlu, İftihar Köksal

Background The optimal duration of treatment for ventilator-associated pneumonia (VAP) remains controversial. Although current guidelines recommend 7-8 days of therapy, many patients receive treatment...

BMC Anesthesiology 2026-04-20 rs-9269769
Ventilator-associated pneumonia short-course therapy individualized treatment antibiotic duration procalcitonin PaO₂/FiO₂ ratio antimicrobial stewardship

Vikas R. Dharnidharka, Asha Moudgil, Priya S. Verghese, Leyat Tal, Rebecca R. Scobell, Mahmoud Kallash, Amy J. Goodwin Davies, Nicole Marchesani, Mitchell G. Maltenfort, Megan Kelton, Margret Bock, Eliza Blanchette, Hillarey K. Stone, Caroline Gluck, Frank Hullekes, Leonardo V. Riella, William E. Smoyer, Mark Mitsnefes, Bradley P. Dixon, Joseph T. Flynn, Michael J.G. Somers, Christopher B. Forrest, Susan Furth, Michelle R. Denburg

Background Recurrence of focal segmental glomerulosclerosis (rFSGS) remains a major complication and a challenge to study treatment efficacy due to lack of granular data in a sufficient sample size. A...

Pediatric Nephrology 2026-04-20 rs-9321284
l segmental glomerulosclerosis kidney transplant pediatrics recurrent disease

Chidiebele Petronilla Ojukwu, Okolo Chukwunonyelum Judith, Fatai Kadiree Ekundayo, Adaeze I Onyekwelu, Chiedozie Eleje, Juliet Ekowa

Background Physical activity (PA) is essential for children’s physical, cognitive, and psychosocial development; however, many children do not meet recommended PA levels, particularly in low- and midd...

BMC Public Health 2026-04-20 rs-8921294
Children Physical activity Parental perceptions School-based physical activity Community participation Nigeria

Jiaee Cheong, Diana S. Chen, William Leung, Cody Chou, Cheryl M. Corcoran, Sinead Kelly, Carrie E. Bearden, Guillermo Cecchi, Justin T. Baker, John M. Kane, Scott W. Woods, Martha E. Shenton, Barnaby Nelson, John Torous

Large language models (LLMs) are increasingly deployed to assess, diagnose, and predict clinical symptoms and outcomes from textual data. However, prior work has shown that LLMs are susceptible to hal...

Research Square 2026-04-20 rs-9394250
automated text analysis clinical safety large language models

Jane Alty, Gianluca Amprimo, Jung Hwan Shin, Max Wuehr, Michal Novotny, Helga Haberfehlner, Claudia Ferraris, Renjie Li, Marcelo Merello, Marina de Koning-Tijssen, Samuel Relton, David Wong, Johannes Taeger, Andreas Zwergal, Sebastian Walther, Jochen Weishaupt, Karl Georg Häusler, Jan Rusz, Babak Taati, Ryan Roemmich, Martin McKeown, Anoopum S. Gupta, Maximilian U. Friedrich

Background: Neurological motor assessment relies on semi-quantitative, scale-based measures with inherent clinimetric limitations that disproportionately affect clinical trials aimed at early disease ...

Research Square 2026-04-20 rs-9437116
Neurology Digital Biomarkers Computer Vision Movement Analysis Videography

Jingshu Fu, Xiaoling Gu, Minyan Yu, Lingna Peng, Jian Song, Xiaoli Sun, Qingxin Wang

Background The predictive value of serum progesterone on the day of endometrial transformation in hormone replacement therapy-frozen embryo transfer (HRT-FET) cycles remains unclear, and its effect ma...

Research Square 2026-04-16 rs-9423110
Hormone replacement therapy Frozen-thawed embryo transfer Progesterone Endometrial transformation Clinical pregnancy Down-regulation
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