2 results found

Xin Zhang, Houjun Jiang, Cheng Chen, Jianhua Ma

Objective To investigates the role of serum interleukin-6 (IL-6) and tumor necrosis factor-α(TNF-α) levels as prognostic biomarkers in patients receiving First-Line Platinum-Based Chemotherapy Combine...

Journal of Cancer Research and Clinical Oncology 2026-04-22 rs-9242248
Non-small cell lung cancer Immunotherapy platinum-based chemotherapy Efficacy prediction Interleukin-6 Tumor necrosis factor-α

Mads Gyrd-Hansen, John Rizk, Frederik Timmermann, Wenxin Lyu, Kit Lee, Majken Kjær, Miriam Beichler, Berthe Fiil, Malin Jessen, Giulia Franciosa, Jesper Olsen, Max Sauerland, Rune Damgaard, Dominik Priesmann

Met1-linked ubiquitin (Met1-Ub) assembled by LUBAC crucially regulates immune receptor signalling. However, the regulation of LUBAC’s function remains widely debated. Here, we reveal that the interact...

Nature Portfolio 2026-04-22 rs-5519483
LUBAC PUB domain Met1-linked ubiquitin OTULIN CYLD SPATA2 TNF immune receptor inflammation cell death immunology
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