SinoXivThe toxicity of nanomaterial is largely determined by particle size, shape, surface charge, composition, concentration, and surface modifications. Due to their nanoscale dimensions, they can interact ...
Background Bladder cancer (BC) is a common urologic malignancy with high recurrence and progression rates, and outcomes for advanced disease remain poor. Peroxisome proliferator-activated receptor gam...
Globally, excessive copper (Cu) absorption in artificially reared calves may increase the risk of excessive hepatic Cu accumulation, likely driven by their elevated pre-ruminant absorptive capacity, w...
The high water Population Drugs, especially antiretroviral drugs, have been widely used worldwide to treat antiretroviral infections and are classified as persistent organic pollutants. These contamin...
Cyclopropylindole-based synthetic cannabinoids, including UR-144, 5F-UR-144 (XLR-11), and XLR-12, represent a structurally atypical subgroup of novel psychoactive substances that remain insufficiently...
Background: The objective of Phase I/II dose-finding design is to determine the Optimal Biological Dose(OBD) that is acceptably safe and demonstrates sufficient anti-tumor activity by maximizing a pre...
