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Open Access Academic Papers from Research Square

2 results found
Research Article in-revision

Residual Tumor Volume Guides Post-Surgical Treatment Paradigm and Need for Salvage Radiotherapy in Vestibular Schwannoma Management

Ansley Unterberger, Alex Devarajan, Jack Zhang, Emery Monnig, Akhil Rao, Mehek Dedhia, George Wanna, Joshua Bederson, Raj Shrivastava

Background and Objectives: Vestibular schwannomas (VS) are slow-growing tumors of the vestibular nerve. Gross total resection (GTR) is recommended for large tumors (> 4cm), brainstem compression, cran...

Journal of Neuro-Oncology 2026-04-23 rs-9305641
Vestibular Schwannoma Adjuvant Radiotherapy Progression-Free Survival Residual Volume Tumor Burden
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Article in-revision

APtamer-Enhanced AP Assay: Dynamic Functional Profiling of Circulating Tumor Materials for Predicting TKI Resistance and Real-Time Treatment Monitoring

Lin Chen, Yue Lu, Panpan Qi, Zhonglin Yang, Dongjiang Tang

The detection of circulating tumor cells (CTCs) is crucial for cancer management but remains challenging due to their rarity and heterogeneity. Alkaline phosphatase (AP) activity, particularly from ca...

Scientific Reports 2026-04-23 rs-8846023
Alkaline Phosphatase Activity Circulating Tumor-Related Materials BG2 Aptamer TKI Resistance Tumor Burden
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