2 results found

Matei mselle

Background Tricuspid Annular Plane Systolic Excursion (TAPSE) is widely used to assess right ventricular (RV) systolic function in children. Its applicability, however, varies across age groups.Object...

Research Square 2026-04-21 rs-9455615
Tricuspid Annular Plane Systolic Excursion Right Ventricular Function Pediatric Echocardiography

Weijia Zhang, Jingyi Chen

Background: The objective of Phase I/II dose-finding design is to determine the Optimal Biological Dose(OBD) that is acceptably safe and demonstrates sufficient anti-tumor activity by maximizing a pre...

BMC Medical Research Methodology 2026-04-21 rs-8852216
Utility Adaptive penalties Toxicity-efficacy Dose-optimization trial
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