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Open Access Academic Papers from Research Square

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Article under-review

Loss of expression of the E3 ligase and tumour suppressor FBW7 attenuates vitamin D signaling

Reyhaneh Salehi Tabar, Aiten Ismailova, Zoe Carter, John H. White

Hormonal 1,25-dihydroxyvitamin D (1,25D) and its analogues signal through the nuclear vitamin D receptor (VDR). While numerous preclinical studies have provided evidence for antiproliferative and anti...

Scientific Reports 2026-04-20 rs-9181172
Vitamin D FBW7 tumour suppressor gene expression profiling pathways analysis cell cycle
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