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Research Article posted

Ginkgolide B improves mitochondrial biogenesis and cognitive deficits through histone H4 lysine 5 acetylation in APP/PS1 mice

Yi-pei Li, Juan Gong, Liu Yang, Rui-rui Peng, Li Jin, Fang Wang, Xiaoyuan Zhao, Li Wang

Ginkgolide B (GB), a diterpenoid lactone compound derived from Ginkgo biloba extract, exhibits anti-inflammatory and inhibits neuroexcitotoxicity. However, its specific pharmacological effects and mec...

Research Square 2026-04-21 rs-9230899
Alzheimer’s disease Ginkgolide B mitochondrial biogenesis histone acetylation amyloidβ
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