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Open Access Academic Papers from Research Square

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Research Article under-review

Ciliary-Enriched and Keratinization-Dominant Endotypes Drive Molecular Heterogeneity in AECOPD

Jiacheng Zhong, Zhen Wang, Hanting Li, Kai Yang, Yu Meng, Shanze Chen, Lingwei Wang

Background: Acute exacerbations of COPD (AECOPD) involve poorly characterized airway host responses. Integrating sputum proteomics with radiomics may reveal underlying molecular heterogeneity and iden...

BMC Pulmonary Medicine 2026-04-20 rs-9347057
AECOPD ciliary proteins immunoglobulins keratins MUC5AC
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