SinoXivObesity-related metabolic disease is linked to impaired adipose tissue function, but the underlying molecular programs are difficult to assign to specific adipose-resident cell types, to mechanistical...
Objectives. This exploratory study aims to characterize metabolic distinctions among men in crafts and labor occupations hypothesized to underlie the shared risk of chronic diseases observed among occ...
Pediatric T-cell acute lymphoblastic leukemia (T-ALL) accounts for approximately 15% of childhood ALL and is associated with a high risk of relapse, with ~ 25% of patients failing conventional therapy...
CRISPR-Cas9 screening enables systematic identification of gene dependencies across diverse cancer cell lines. However, distinguishing lineage-specific vulnerabilities from broadly essential genes rem...
Dietary sugars differentially influence hepatic lipid metabolism, yet the metabolism of galactose—the monosaccharide unique to lactose—remains poorly defined in humans. Here, using stable isotope trac...
