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Open Access Academic Papers from Research Square

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Research Article under-review

Developing a Modular MicroRNA Biosensor in E. coli for Early Cancer Diagnosis

Yaman Yazici

Early diagnosis of cancer can be facilitated by detecting microRNA (miRNA) biomarkers that are dysregulated during tumor development. Here we present a general-purpose whole-cell biosensor platform fo...

Discover Medicine 2026-04-23 rs-9023138
microRNA biosensor synthetic biology toehold switch CRISPR Cas13 whole-cell sensor cancer diagnostics
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