2 results found

Shiva Rama Krishna Muppalla, Kishore Babu Bonige

Sunitinib (SUNI) is a small-molecule tyrosine kinase inhibitor with limited water solubility, extensive first-pass metabolism, and low oral bioavailability, restricting its therapeutic efficacy. This ...

BioNanoScience 2026-04-22 rs-9348532
Sunitinib Cubosomes Box Benkhen design GMO Bioavailability

Abdi Leta, Gamachu Diba

Background Oral administration is the preferred route for drug delivery due to convenience and patient compliance, yet its efficacy is hampered by low solubility and enzymatic degradation. Nanoparticu...

Research Square 2026-04-21 rs-9452361
nanoparticles oral bioavailability drug delivery systems pharmacokinetics
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