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results found
Sunitinib (SUNI) is a small-molecule tyrosine kinase inhibitor with limited water solubility, extensive first-pass metabolism, and low oral bioavailability, restricting its therapeutic efficacy. This ...
Sunitinib
Cubosomes
Box Benkhen design
GMO
Bioavailability
Background Oral administration is the preferred route for drug delivery due to convenience and patient compliance, yet its efficacy is hampered by low solubility and enzymatic degradation. Nanoparticu...
nanoparticles
oral bioavailability
drug delivery systems
pharmacokinetics
SinoXiv