69 results found

Zhaoli Meng, Yuhao Tang, Tianying Sun, Man Chen, Hongsheng Ren, Chunting Wang, Qizhi Wang, Huimin Hou, Wei Fang

Background Acute fatty liver of pregnancy (AFLP) is a rare, life-threatening obstetric emergency. Early prediction of its severe postpartum complications remains a significant clinical challenge, opti...

BMC Pregnancy and Childbirth 2026-04-24 rs-9166440
Acute fatty liver of pregnancy MELD score APACHE II SOFA postpartum complications decision curve analysis

Jianfei Wang, Tianci Hu, Minjie Zhao, Chunrong Wu

Objectives: To identify independent risk and protective factors for acupuncture response in community-dwelling patients with chronic low back pain, and to develop and validate a clinical prediction mo...

BMC Health Services Research 2026-04-23 rs-9046927
Chronic Low Back Pain Acupuncture Prediction Model Traditional Chinese Medicine Syndrome Pattern Nomogram

Kumar Kulldeep Niloy, Jamie Horn, Nazmul Hasan Bhuiyan, Suhas S. Bhosale, Khaled A. Shaaban, Thomas E. Prisinzano, Jon S. Thorson, Jurgen Rohr, Markos Leggas

Purpose To develop and verify a physiologically based pharmacokinetic (PBPK) modeling strategy for mithramycin (MTM) and its analog, MTMSA-Trp, with the aim of projecting first-in-human plasma pharmac...

Cancer Chemotherapy and Pharmacology 2026-04-23 rs-9488905
Physiologically based pharmacokinetic model First-in-human dose prediction Interspecies scaling Mithramycin analog Ewing sarcoma

Darley Sackitey, Vanessa Oguamanam, Rebecca Tafete, Keianna Moyer, Precious Ajiero, Oluyemi Farinu, Sierra Carter, Muhammed Y. Idris, Natalie Hernandez, Rasheeta Chandler, Andrea Grimes Parker

With Black women facing disproportionately worse health outcomes during and after pregnancy, innovations in digital mental health provide an avenue to support the mental wellbeing of this population. ...

npj Women's Health 2026-04-23 rs-9062051
maternal mental health Black women digital mental health stress coping mental health prediction

Zhi-Qin Fang, Shao qiang Qin, Tian-Shu Gu, Su-Tao Hu, Yu-Kun Zhang, Xian Shao, Tong Liu, Kang-Yin Chen

Objective:This study sought to develop and validate a nomogram incorporating clinical factors and complete blood count (CBC)-derived inflammatory indices, designed to predict all-cause mortality in di...

Scientific Reports 2026-04-23 rs-8894211
acute myocardial infarction diabetes complete blood count (CBC)-derived inflammatory indices predict nomogram

Nattapon Wongworapanya, Panarat Noiperm, Pirun Saelue

Background Kidney biopsy is an essential procedure for diagnosing kidney diseases. However, bleeding remains a major complication. This study aimed to evaluate predictive factors, including platelet a...

Research Square 2026-04-23 rs-9347196
prediction model thromboelastography platelet aggregation kidney biopsy bleeding complications

Wei Chen, Wenhua Xie, Jing Jin, Yifang Cao, Li Guo, Linfeng Lu, Yanqin Gu, Siyu Lei, Wei Zhu, Yi He

Background Transurethral resection of bladder tumor (TURBT) is the standard treatment for non-muscle-invasive bladder cancer (NMIBC), but the high rates of residual tumor and recurrence remain major c...

World Journal of Surgical Oncology 2026-04-23 rs-9223803
UroCAD bladder cancer TURBT chromosomal instability recurrence

Lin Chen, Yue Lu, Panpan Qi, Zhonglin Yang, Dongjiang Tang

The detection of circulating tumor cells (CTCs) is crucial for cancer management but remains challenging due to their rarity and heterogeneity. Alkaline phosphatase (AP) activity, particularly from ca...

Scientific Reports 2026-04-23 rs-8846023
Alkaline Phosphatase Activity Circulating Tumor-Related Materials BG2 Aptamer TKI Resistance Tumor Burden

Wenyan Jian, Ruojin Yao, Yanhua Zhao, Mi Pei, Wenjing Yong, Gang Chen, Yimei Fu, Ronghui Tang, Fuyan Tan, Dewei Guo

Background Predicting the need for early postnatal surgery in severe fetal unilateral hydronephrosis remains challenging. Traditional fetal urinary electrolyte thresholds, derived from end-stage renal...

BMC Pregnancy and Childbirth 2026-04-23 rs-9343823
unilateral hydronephrosis fetal pyelocentesis fetal urine electrolytes fetal renal severity index principal component analysis anteroposterior diameter

Abdi Hayato, Tesfa Gebremeskel, Solomon Tejineh

Background: Antimicrobial resistance (AMR) is a major threat in pediatric intensive care units (PICUs). Data on resistance patterns in non-neonatal pediatric cohorts in Ethiopia remain scarce. This st...

BMC Pediatrics 2026-04-23 rs-9163036
Antimicrobial resistance Pediatric ICU Microbial profile Ethiopia High-risk AMR
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