69 results found

Yan Jun Lin

Background: Mutations in intermediate filament genes cause over 100 human diseases, yet predicting clinical severity from genotype remains unreliable due to phenotypic variability and the prevalence o...

Human Genetics 2026-04-21 rs-9257849
intermediate filament FoldX ΔΔG variant interpretation genotype–phenotype correlation protein stability

Murat Uçar, Nureddin Raym, Uğur Soy, Erkan Karadağ, Murat Topçuoğlu, Ali Akkoç

Purpose To evaluate the prognostic value of preoperative hemoglobin-lymphocyte-neutrophil ratio (HLNR) and hemoglobin-lymphocyte-platelet ratio (HLPR) for predicting tumor recurrence at control cystos...

SN Comprehensive Clinical Medicine 2026-04-20 rs-9342974
Hematologic tests Prognosis Transitional Cell Carcinoma Urinary Bladder Neoplasms

Hongyi Yi, Yu-peng Zheng, Shengjun Fang, Mian Yang, Bo Zhou, Jiazi Yu

Background Optimal observation periods and surgical predictive utility for iohexol in adhesive small bowel obstruction (ASBO) remain undefined. This study systematically evaluates iohexol's time-depen...

World Journal of Emergency Surgery 2026-04-20 rs-9334871
Adhesive Small Bowel Obstruction Water-soluble Contrast Iohexol Meta-Analysis

Misaki Akiyama, Kentaro Nishi, Toshihiro Matsui, Kaoru Tsuboi, Satoshi Okada, Tomoya Kaneda, Masao Ogura, Chiba Hirotaka, Norihiko Tsuboi, Kentaro Ide, Shotaro Matsumoto, Koichi Kamei

Background and hypothesis: Pediatric acute kidney diseases and disorders (AKD) are a new concept defined as kidney damage lasting 7–90 days from onset. Data on AKD after bloodstream infection are limi...

Pediatric Nephrology 2026-04-20 rs-9332681
acute kidney injury acute kidney disease bacteremia pediatric sepsis

Qingkai Wang, Hao Qiu, Liran Shen, Jinxing Dai, Fachen Miao, Qianjin Shi, Yunbiao Zhang, Kang Shen, Weibing Qiu

Objective IgA vasculitis nephritis (IgAVN) plays a decisive role in the long-term prognosis of pediatric IgA vasculitis (IgAV), yet the temporal lag of routine urinalysis frequently hinders early and ...

Research Square 2026-04-20 rs-9261325
IgA vasculitis IgA vasculitis nephritis Machine learning Risk strat-ification

Ludmilla Ferreira Justino, David Henriques Matta, Marcos Vinício Cesario dos Santos, Luís Fernando Stone, Daniel Castro, Santiago Vianna, Alexandre Bryan Heinemann

The El Niño-Southern Oscillation (ENSO) is a major driver of climate and agricultural productivity variability, as those events modulate significant fraction of rainfall and air temperature interannua...

Theoretical and Applied Climatology 2026-04-20 rs-9314260
Random Forest Climate variability Predictive modeling Functional data analysis

Xiao Zhou, Yuze Sun, Jie Wu, Xiaomeng Huang

The Madden-Julian Oscillation (MJO) is an important driver of global weather and climate extremes, but its prediction in operational dynamical models remains challenging, with skillful forecasts typic...

Climate Dynamics 2026-04-20 rs-9352677
Madden-Julian Oscillation Deep learning Bias correction Explainable AI

Jingshu Fu, Xiaoling Gu, Minyan Yu, Lingna Peng, Jian Song, Xiaoli Sun, Qingxin Wang

Background The predictive value of serum progesterone on the day of endometrial transformation in hormone replacement therapy-frozen embryo transfer (HRT-FET) cycles remains unclear, and its effect ma...

Research Square 2026-04-16 rs-9423110
Hormone replacement therapy Frozen-thawed embryo transfer Progesterone Endometrial transformation Clinical pregnancy Down-regulation

Igor Rouzine

Some viruses persist in a population, because their rapid evolution allows them to escape recognition by antibodies in previously-infected individuals. To investigate parameters of effective vaccinati...

Research Square 2025-09-17 rs-7526496
vaccination broadly-neutralizing virus evolution model
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