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Open Access Academic Papers from Research Square

2 results found
Research Article under-review

Dose Dependent Toxicity of Carbon Nanosphere in Drosophila melanogaster: Establishing Safe Limits for Biomedical Application

Samantha Raj Sah, Anisha Saha, Sahabudeen Sheik Mohideen, Balashanmugan Pannerselvam, G. Devanand Venkatasubbu

The toxicity of nanomaterial is largely determined by particle size, shape, surface charge, composition, concentration, and surface modifications. Due to their nanoscale dimensions, they can interact ...

Chemical Papers 2026-04-23 rs-9216375
Carbon nanosphere Drosophila melanogaster Reactive Oxygen Species Risk assessment Toxicity
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Article under-review

Chemical modification of pyrroloquinoline quinone identifies a monomethyl ester derivative that enhances DUOX activation and causes lethality in C. elegans

Hiroyuki Sasakura, Moribe Hiroki, Kazuto Ikemoto, Masashi Ikeno, Yuki Morioka, Yuka Takeuchi, Kosei Takeuchi

Pyrroloquinoline quinone (PQQ) is a multifunctional natural coenzyme that plays important roles in innate immunity, nutritional physiology, and redox biology, including the activation of dual oxidases...

Scientific Reports 2026-04-22 rs-9310397
Pyrroloquinoline quinone (PQQ) chemical modification monomethyl ester dual oxidase (DUOX) reactive oxygen species Caenorhabditis elegans
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