Paper List

Huiqing Yuan, Huanmin Niu, Xiaoxue Zheng, Yuhao Sun, Qi Sun, Qiqi Lu, Mengqi Jia

The autophagy-lysosome pathway, governed by transcription factor EB (TFEB), is critical in cellular degradation and signal transduction. Dysregulation of this pathway or TFEB contributes to aging, tum...

Qi Wu, Zhijie Gao, Wei Pei, Ping Wang, Xin Yu, XinXin Rao, Ye Yao, Zhiyuan Liu, Ruiqing He, Enming Tian, Yanrong Yang, Bei Li, Tingting Niu, Yunqing Liu, Zhiyu Li, Hongmei Zheng, Heping Zhang, Oliver Kepp, Guido Kroemer, Lan Fang, Ping Wang

Subnuclear compartmentalization has emerged as a critical determinant of transcriptional homeostasis and cell-fate determination. The nucleolus scaffolds specialized heterochromatin, yet the mechanism...

Mads Gyrd-Hansen, John Rizk, Frederik Timmermann, Wenxin Lyu, Kit Lee, Majken Kjær, Miriam Beichler, Berthe Fiil, Malin Jessen, Giulia Franciosa, Jesper Olsen, Max Sauerland, Rune Damgaard, Dominik Priesmann

Met1-linked ubiquitin (Met1-Ub) assembled by LUBAC crucially regulates immune receptor signalling. However, the regulation of LUBAC’s function remains widely debated. Here, we reveal that the interact...

Mohan Su, can Cao, fulin sun, Liangqian jiang, Fanghao Yang, Huhu Zhang, Xiaoze Zhang, Ruixuan Wang, Ziyuan Wen, chunjuan yu, Yiming Wang, Lina Yang, Zhe Zhang, bing li

Overcoming oxidative stress is a critical mechanism by which breast cancer cells sustain malignant progression and therapeutic resistance. However, the specific regulatory networks governing this adap...