471 results found

Vaishali Chaurasiya, Luyang Li, Aina Lluch, Ana Fernández-Sánchez, Jukka Harju, Dan Duc Pham, Sanni Perttunen, Salla Keskitalo, Markku Varjosalo, Kirsi H. Pietiläinen, P.A. Nidhina Haridas, José-Maria Moreno-Navarrete, José I. Rodríguez-Hermosa, Encarna Piedrafita-Serra, Asha Kar, Päivi Pajukanta, Markku Laakso, Ville Männistö, Jussi Pihlajamäki, Minna U. Kaikkonen, Gema Frühbeck, Oriol A. Rangel-Zúñiga, Francisco José Tinahones, Carlos Dieguez, Ralph Burkhardt, Marcus Höring, Gerhard Liebisch, Johanna Pörschke, María Gómez-Serrano, Johannes Graumann, Witold Szymanski, José-Manuel Fernández-Real, You Zhou, Vesa Olkkonen, Francisco Ortega

Obesity-related metabolic disease is linked to impaired adipose tissue function, but the underlying molecular programs are difficult to assign to specific adipose-resident cell types, to mechanistical...

Research Square 2026-04-23 rs-9485802
Adipose tissue adipocyte endothelial cell proteomics lipidomics meta-inflammation obesity weight loss

Hongmin Yu, Tao Wang, Xiaomei Chen, Cheng Zhang, Qing Xu, Meixia Huang, Yingzheng Wang, Jie Xu, Yinghao Wang

Motherwort (MW) is known for its renoprotective effects, but it has also been reported to potentially cause kidney damage. This study aimed to explore the distinct mechanisms underlying the protective...

Scientific Reports 2026-04-23 rs-8740889
motherwort ferritinophagy EGFR pathway oxidative stress apoptosis

Rameswari Poornima Janardanan, Elamir A. Osman, Omer O. Saeed, Mahmoud Eltahir Ali, Omer Gaddoura

Purpose Cerebral microbleeds (CMBs) are critical imaging biomarkers for small vessel disease, but detection remains challenging due to small lesion size, variable MRI appearance, and annotation burden...

Research Square 2026-04-23 rs-9496185
Cerebral micro-bleeds self-supervised learning magnetic resonance imaging deep learning medical image analysis

Olena Usachova, Gennadiy Lezhenko, Olena Pashkova, Anastasiia Tovma, Yelyzaveta Silina, Kateryna Samoylyk

Background Streptococcus pyogenes (group A β-haemolytic streptococcus, GAS) is a common cause of infections in children; however, invasive forms involving the central nervous system are extremely rare...

Research Square 2026-04-23 rs-9447959
children meningitis sinus disease bacterial infections Streptococcus pyogenes complications subdural empyema diagnosis treatment

Wendy Nieto-Gutierrez, Melixa Medina-Aedo, M Soledad Isern Val

Background This review identifies and describes clinical prioritisation tools used to rank patients on surgical waiting lists for cataract surgery, knee replacement, and inguinal hernia repair, and ev...

Research Square 2026-04-23 rs-9447805
waiting lists cataract extraction arthroplasty replacement knee herniorrhaphy (source: MeSH)

Burhan Ulhaq, Tehniat Khaliq, Simon John, Saadia Ziaulhaque, Siraj Ulhaq

Background: Primary extracranial meningiomas are rare neoplasms that may arise without intracranial or dural involvement and are frequently misdiagnosed as benign scalp lesions. Lack of routine histop...

Research Square 2026-04-23 rs-9498731
extracranial meningioma scalp tumor meningothelial meningioma recurrence en bloc excision

Nihal Kaya, Şerife Şahin, Alper Külçü, Gizem Tırıs

Background This in vitro study evaluated monomer release from different light-cured composites used for clear aligner attachments over time, assessing the effects of composite type, attachment size an...

BMC Oral Health 2026-04-23 rs-9160597
attachment clear aligner monomer elution

Masanobu Yamazaki, Sahoko Ninomiya, Akihito Hashizume, Teppei Takeshima, Hiroki Ito, Kazuhide Makiyama, Hiroji Uemura, Jun-ichi Teranishi, Takashi Kawahara

Background About half of both men and women have lower urinary tract symptoms, and aging is reported to have a significant impact on these symptoms. Lifestyle-related diseases such as diabetes, hypert...

BMC Urology 2026-04-23 rs-9310496
Lower Urinary Tract Syndrome Depression Japanese Men Questionnaire

Xin Liu, Wenrui Zhu, Xingui Li

Automated pain monitoring devices are critical for effective patient care, particularly for non-communicative individuals in intensive care and post-operative settings. This paper presents the develop...

Scientific Reports 2026-04-23 rs-9310940
medical device system pain assessment facial expression recognition surface electromyography multi-modal fusion clinical deployment healthcare monitoring

Felipe Webster-Cordero, Lydia Giménez-Llort

The presence of subjective cognitive complaints (SCC) in older adults, especially at the executive level, is a major reason for consultation in clinical practice. These changes, though often subtle, m...

BMC Neurology 2026-04-23 rs-9059640
Subjective cognitive complaints Dementia Executive performance Neuropsychological assessment self- and informant report
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