497 results found

Ulka Vaishampayan, Jeremy (M. G.) Taylor, Deepak Kilari, Tanya Dorff, Alexandra Sokolava, Yaxuan Huang, Phillip Palmbos, Jacqueline Brown, Irene Tsung, Megan Caram, Sarah Yentz, Bassel Nazha, Zachery Reichert, Joshi Alumkal

Background: Effective therapies remain a currently unmet need for neuroendocrine prostate cancer (NEPC). Preclinical synergy in small cell cancer, and clinical tolerability led to the conduct of a mul...

Nature Portfolio 2026-04-23 rs-9471666
immune checkpoint therapy anti-vascular therapy small cell prostate cancer

Alon Gorenshtein, Mahmud Omar, Yiftach Barash, Jonathan B. Kruskal, Muneeb Ahmed, Olga R. Brook, Ben Illigens, Girish N. Nadkarni, Eyal Klang

Large language models are increasingly used in clinical medicine, but their reliance on cloud servers conflicts with patient-privacy requirements and excludes resource-limited healthcare systems. Smal...

Research Square 2026-04-23 rs-9488729
Small Language Models Agentic AI Large Language Models Systematic Review Clinical Natural Language Processing Edge Deployment PRISMA

Weichuan Yu, Chen Zhou, Shengzhi Lai, Shuaijian Dai, Peize Zhao, Ning Li

Cross-linking mass spectrometry (XL-MS) is a technique for investigating protein-protein interactions (PPIs) and protein structures. In the realm of biology, post-translational modifications (PTMs) pl...

Research Square 2026-04-23 rs-5215565
cross-linking mass spectrometry post-translational modifications peptide identification database search

Shiyuan Dong, Peibo Sun, Jianrong Cai, Aoji Zhu, Zhenning Zhou, Tianqi Huang, Hongen Liao, Zhengkun Yi, Lidong Yang, Fang chen

Restoring haptic feedback remains a major challenge in robot-assisted minimally invasive surgery (RMIS), especially for localizing subsurface tumors and estimating their depth. This paper presents a c...

npj Robotics 2026-04-23 rs-9278913
Fiber Bragg grating sensor array robotic palpation time-series transformer tumor depth estimation

Yun Chen, Jinlin Wu, Jia Qin, Chenxu Gao

To overcome shortcomings that rocking steel frame structures require numerous internal self-centering joints and corresponding rocking interfaces, and reducing the special design requirements for infi...

Bulletin of Earthquake Engineering 2026-04-23 rs-9105509
Integral rocking Self-centering Deformation mode Rocking layer Shaking table test

Xi Chen, Zexu Wei, Ranran Yu, junnan Xu, Chenyu Tao, Aixia Zhang, Longjie Li, Xiaoshan Zhang, Jin He, Jiajun Yu, Xuhuang Xiao, Jiahui Guo, Tong Wang, Wei Gong, Yanbo Wang, Chen-Yu Zhang, Dijun Chen, Zhang-Peng Chen, Chenbo Ji

Postnatal depression (PND) increases the risk of neurodevelopmental impairments in offspring, yet the underlying mechanisms remain elusive. Here, we identify an intergenerational signaling pathway thr...

Research Square 2026-04-23 rs-9008493

Sara Pires, Lapo Mughini-Gras, Sandra Hoffmann, Kunihiro Kubota, Shannon Majowicz, Martyn Kirk, Lucy Robertson, Paul Torgerson, Lea Jakobsen, Antonio Agudo, Li Bai, Tety Rachmawati, Yuki Minato, Charlee Roberts, Arie Havelaar, Brecht Devleesschauwer, Elisa Benincà, Robin Lake, Tine Hald, Roger Cooke, Willy Aspinall, Gabriela Nane

Identifying the sources of foodborne diseases is crucial for guiding national food safety strategies and supporting policies that promote safe and sustainable diets. We present global estimates of the...

Research Square 2026-04-23 rs-9449162

Chao Yang, Jie Ye, Yixuan Li, Xinyi He, Yuqin Liang, Qin Meng, Qinzheng Zhou, Lu Liu, Jin-Song Zhang, Jun Liu

Rice employs sophisticated and multilayered regulatory networks to precisely modulate innate immune responses against diverse pathogens. Although post-transcriptional control has emerged as a vital la...

Nature Portfolio 2026-04-23 rs-9320279
GYF domain RNA-binding protein NLR translation phosphorylation rice immunity

Reiko Oda, Zakaria Anfar, Masahiro Nakaya, Wijak Yospanya, Simon Poly, Yann Battie, Yutaka Okazaki, Walid Baaziz, Ovidiu Ersen, David Talaga, Thierry Buffeteau, Matthias Pauly, Nanami Hano, Marco Bertuolo, Pamela DE LA FUENTE, Sylvain Nlate, Emilie Pouget, Kuniaki Murase, Kazuhiro Fukami

The bottom-up synthesis of three-dimensional chiral metallic nanostructures without molecular chiral ligands remains a fundamental challenge. Here we report a template-confined, ligand-free strategy p...

Nature Portfolio 2026-04-23 rs-9308726

BASHIR SHUAIBU AHMAD, Dr. Naveen Kumar Yadav, Dr. Muhyiddeen Yahaya Musa, Dr. Mukeesh Kumar

This paper presents a systematic simulation-based framework for comparing the structural performance and energy efficiency of robotic arm links fabricated from Aluminium 6061-T6 and Carbon Fiber Reinf...

Research Square 2026-04-23 rs-9459718
CFRP Robotic manipulator Energy efficiency Lagrangian dynamics Structural optimization Composite materials MATLAB simulation
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