761 results found

Susan Logue, Gideon Ong, Masozi Palata, Suraj Shaji, Joel Pearson

The Unfolded Protein Response (UPR) is a conserved network of signaling pathways controlled by the Endoplasmic Reticulum (ER) anchored stress sensors IRE1, PERK and ATF6. The UPR’s primary function is...

Cell Death & Disease 2026-04-21 rs-9373070
Endoplasmic Reticulum Stress Unfolded Protein Response ATF6 IRE1

Soroush Vahidi

Deriving global rankings from noisy and incomplete pairwise comparisons is a fundamental problem with applications in sports analytics, preference aggregation, and evaluation. Many recent approaches r...

Research Square 2026-04-21 rs-9281720
Ranking Pairwise comparisons Feedback arc set Directed graphs Training-free methods

Jackson Beem, Amine Barrak, Emna Ksontini

Large language models are increasingly embedded across the DevOps pipeline, from planning and code generation to testing and deployment, yet multi-agent LLM pipelines remain opaque: errors propagate s...

Automated Software Engineering 2026-04-21 rs-9350097
Multi-agent LLM pipelines Role specialization Accountability Traceability Code generation Execution-based verification Pipeline design

Oded Shor, Felix Benninger, Abraham Weizman, Andrei Khrennikov

Dendrogramic Holographic Theory (DHT) is a purely relational theory of information in which the primitive elements are events, and physical description is defined by an observer’s dendrogram: a hierar...

Scientific Reports 2026-04-21 rs-9215728
relational information dendrograms p-adic topology exchange symmetry bosons fermions Pauli exclusion principle Minkowski-like spaces

Akis Kourtis, Achilleas Economopoulos, George Xilouris, Evangelos Markakis

The proliferation of Internet of Things (IoT) devices operating in swarm-like formations—from autonomous device fleets to federated service networks— demands a computing continuum that spans edge node...

Discover Internet of Things 2026-04-21 rs-9232592
service mesh scalability IoT-to-cloud continuum tail latency benchmarking Istio microservices sidecar proxy overhead Fortio Kubernetes cloud-native performance

A.A.L.C. Perera, K.M.R.D. Abhayapala, P.N.M.S. Piyarathne, S.M.C.M Samarakoon, P.D. Abeythilakarathe

This study systematically evaluated the agronomic viability of a novel double-cropping system through heterografting between tomato (Solanum lycopersicum L.) and potato (Solanum tuberosum L.). Using c...

Potato Research 2026-04-21 rs-9199706
Double-cropping Heterografting Land-use efficiency Protected cultivation Solanum lycopersicum Solanum tuberosum

Rogelio Hasimoto-Beltran, Enya Tovar-Estrada

Current encryption systems face increasing challenges from ever more sophisticated attacks, motivating the exploration of alternative schemes that offer stronger security and higher performance. In th...

Scientific Reports 2026-04-21 rs-9271718
Chaotic Cryptography Predator-Prey Model Group Chase-Escape Rényi Map

Weijia Zhang, Jingyi Chen

Background: The objective of Phase I/II dose-finding design is to determine the Optimal Biological Dose(OBD) that is acceptably safe and demonstrates sufficient anti-tumor activity by maximizing a pre...

BMC Medical Research Methodology 2026-04-21 rs-8852216
Utility Adaptive penalties Toxicity-efficacy Dose-optimization trial

Ahmed Elsayed Abdelfattah, Mohamed Seifeldin, Mohamed Mostafa Fouad

Network intrusion detection systems play a vital role in safeguarding digital infrastructure. Still, significant challenges persist due to the highly imbalanced nature of network traffic and the lack ...

Scientific Reports 2026-04-21 rs-9108130
Intrusion Detection System Deep Learning for Cybersecurity Transformer Model Class Imbalance Learning Explainable Artificial Intelligence Network Traffic Analysis

Mandy Gijzen, Bertus Jeronimus, Diana Bergen, Albertine J Oldehinkel

Background Suicide is a leading cause of death among adolescents and emerging adults. Suicidality is a multidimensional construct that includes suicidal ideation (SI), self-harm (SH), suicide attempts...

BMC Pediatrics 2026-04-21 rs-9314087
Suicidality Remission Protective factors Epidemiology Longitudinal cohort
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