As a transitional space that connects urban and rural elements, the mobility behavior of peri-urban residents is key to understanding the mechanisms of urban–rural interaction and the logic of spatial...
Phase II trial of Pembrolizumab and Lenvatinib in Advanced Neuroendocrine Prostate Cancer (PLANE-PC)
Background: Effective therapies remain a currently unmet need for neuroendocrine prostate cancer (NEPC). Preclinical synergy in small cell cancer, and clinical tolerability led to the conduct of a mul...
Large language models are increasingly used in clinical medicine, but their reliance on cloud servers conflicts with patient-privacy requirements and excludes resource-limited healthcare systems. Smal...
Cross-linking mass spectrometry (XL-MS) is a technique for investigating protein-protein interactions (PPIs) and protein structures. In the realm of biology, post-translational modifications (PTMs) pl...
Identifying the sources of foodborne diseases is crucial for guiding national food safety strategies and supporting policies that promote safe and sustainable diets. We present global estimates of the...
Background: The prevalence of suicidal behavior in children and adolescents is a critical public health issue, with rates in the coffee region exceeding the national average. This study analyzed respo...
The rational synthesis of high-performance inorganic two-dimensional (2D) nonlinear optical (NLO) crystals remains challenging because wide bandgaps, large birefringence, and strong second-harmonic ge...
Introduction: Prior literature demonstrates that in patients with blunt femoral shaft fractures, ipsilateral femoral neck fractures occur at a rate of 1-9% and can be challenging to diagnose. Ballisti...
Purpose Endoscopic variceal ligation (EVL) - induced ulcer bleeding occurs rarely after variceal ligation, but is potentially life-threatening. Limited data exist regarding incidence across different ...
Introduction: The teaching and practical training of future doctors plays an important role in the university curriculum. Material and techniques: At the Women's Clinic of Saarland University Hospital...
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