8 results found

Mia S. Tackney, Amber Steele, Marie-Louise Zeissler, Sofía S. Villar, Jeremy Dearling, Sarah Markham, Farheen Yameen, Community Involvement Group for Digital Outcomes (CIG-DO)

Background Analysis of clinical trials with missing data requires statistical assumptions. When novel digital outcome measures are used, it is particularly important to understand trial participants’ ...

BMC Medical Research Methodology 2026-04-22 rs-9293900
missing data patient and public involvement and engagement digital outcome measures trial conduct

Paolo Melidoro, Steven E. Williams, Gregory Y.H Lip, Magdalena Klis, Oleg Aslanidi, Adelaide Vecchi

Atrial fibrillation (AF) is the most common cardiac arrhythmia and increases stroke risk and reduces quality of life. Left atrial catheter ablation (LACA) restores sinus rhythm by targeting abnormal e...

Research Square 2026-04-22 rs-8745185

Yuri Russo, Edward Nyman Jr, Agne Straukiene, Elliot Winch, Jiaxi Ye, Phaedra Leveridge, Melvyn Roerdink, William Young

Background: Multiple sclerosis (MS) commonly affects balance and mobility, yet routine clinical tests may lack sensitivity to subtle change. Standardized mobility assessments such as the Timed Up and ...

Research Square 2026-04-22 rs-9424668
multiple sclerosis augmented reality digital biomarkers gait analysis wearable sensors home assessment Romberg TUG 6-minute walk test

Ross Mallett, Jade Jenkinson

Background Diagnostic imaging is frequently requested for non-specific low back pain despite limited clinical value. Patient desire for imaging remains a key driver of low-value referrals, yet little ...

BMC Musculoskeletal Disorders 2026-04-22 rs-8871658
Non-specific low back pain Diagnostic imaging Patient beliefs Imaging desire Expectations Shared decision-making Qualitative research Interpretative phenomenological analysis

Lily C. Farrell, Justin C. Muste, Atharva Hudlikar, Xin Ying Rachel Song, Pearse A. Keane, Rupesh Agrawal, Jose S. Pulido

Background: To systematically characterize foveal architecture and choroidal morphology in KIF11-associated retinopathy using multimodal imaging, and to assess for pachychoroid features using quantita...

International Journal of Retina and Vitreous 2026-04-21 rs-9361112
KIF11 Choroid Pachychoroid Choroidal vessels Choroidal vascularity index Inherited retinal disease

Harrison Phillips, Majid Ali Qureshi, Abdul Jalil, Mehtab Khan, Christy Collins, Omar Hafeez-Bore

Background Ludwig’s angina is a life-threatening cellulitis that can easily progress to airway compromise. Significant infection, often from periodontal abscesses of the molar teeth, may cause superio...

Journal of Emergency and Disaster Medicine 2026-04-21 rs-9381862
Emergency medicine intensive care critical care Ludwig’s angina Airway compromise Le Mierre’s disease dental abscess

Adewunmi Akingbola, Abiodun Adegbesan, Emmanuella Benson, Mmaduabuchi Ozioko, Khalil-uh-Rahman Abdullah, Maxwell Boakye, Olajumoke Adewole, Petra Mariaria

Introduction The Hepatitis B third dose (HepB3) vaccination is essential in preventing chronic infections, liver failure, and cancer. Despite progress, global coverage remains uneven, especially in lo...

Research Square 2026-04-21 rs-9379366
Hepatitis B third-dose vaccine spatiotemporal analysis global coverage regression model choropleth maps

Patrick Kierkegaard, Bowen Su, Hilary Stobart, Lesley Stephen, Szeyi Ng, Lucy Kilburn, Charlotte E. Coles

Background Patient-initiated follow-up within personalised stratified follow-up replaces some routine appointments with supported self-management and a route back to specialist care or relevant suppor...

International Journal for Equity in Health 2026-04-20 rs-9162255
Breast cancer survivorship health equity patient‑initiated follow‑up administrative burden navigation access to care NHS qualitative research
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