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Open Access Academic Papers from Research Square

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Research Article under-review

Integration of bulk and single-cell RNA-seq data identifies a cellular senescence-related prognostic signature in liver hepatocellular carcinoma

Rentong Liu, Bing Li, Yiqian Luo, Xiuwei Yan, Yuanyuan Wang, Song Jiang, Chengjie Gan, Yiwei Cheng

Liver Hepatocellular carcinoma (LIHC) is a highly heterogeneous malignancy with poor prognosis, underscoring the urgent need for reliable biomarkers and therapeutic targets. Cellular senescence plays ...

Discover Oncology 2026-04-23 rs-9198475
Hepatocellular carcinoma Cellular senescence Prognostic signature Tumor microenvironment
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