29 results found

Steffen Hackbarth, Muriel Kabus, Xiuli Zheng, Tong Mu, Ronald Sroka, Weimin Liu

Objective Photosensitization by singlet oxygen is a chemical reaction with cellular quenchers, mainly proteins. Therefore, optical detection of singlet oxygen in cells affects the investigated cells a...

Photochemical & Photobiological Sciences 2026-04-21 rs-9130479

Md Rakibul Islam, Riad Hassan, Abdullah Nazib, Feroza Naznin, MD ZAHIDUL ISLAM, Clinton Fookes

Deep learning has achieved remarkable accuracy in medical image segmentation, particularly for larger structures with well-defined boundaries. However, its effectiveness can be challenged by factors s...

Scientific Reports 2026-04-21 rs-8651167

Yanchu Tong, Wenkui Chen, Shun Deng, Lu Qin

Objective: To investigate the role of DISP3 in thyroid cancer (TC) progression and its modulation of the tumor immune microenvironment. Methods: Bioinformatics analyzed DISP3 expression and its progno...

Research Square 2026-04-21 rs-9394485
DISP3 Thyroid cancer Tumor immune microenvironment Macrophage polarization dendritic cell

Yumeng Mao, Irineos Papakyriacou, Yonglin Lu, Liam Alford

Acute myeloid leukemia is an aggressive hematological disease, where cancer cells down-regulate antigen presentation and immune-stimulatory molecules. Here, we show that genetic deletion of protein ne...

Leukemia 2026-04-21 rs-9399910
Protein neddylation Toll-like receptors Myeloid cells Leukemia Tumor Immunology

Riya Albert, Joshua Thomas, Navid Sadeghi, Sangeetha Reddy, Glenda Delgado, Heather McArthur, Samira Syed, Deborah Farr, Nisha Unni

Introduction Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by poor prognosis. Based on the KEYNOTE-522 trial, neoadjuvant pembrolizumab plus chemotherapy has become the s...

Breast Cancer Research and Treatment 2026-04-21 rs-9096569
tumor-infiltrating lymphocytes triple-negative breast cancer neoadjuvant therapy immunotherapy pathological complete response

Chang Ge, Wenjie Zhang, Pengcheng Zhang, Jingxuan Xu

Background: High-grade glioma is a highly malignant primary tumor of the central nervous system characterized by a poor clinical prognosis. The regulatory mechanisms of astrocytes within its TME are n...

European Journal of Medical Research 2026-04-21 rs-9156282
High-grade glioma Astrocytes Tumor microenvironment Prognostic marker Immune infiltration Cell-cell communication

Minxin He, Haibin Zhou, Xiangyu Wang, Mingrui Li, Tie Chong

Purpose: Early diagnosis of tumor recurrence or metastasis is critical for prolonging survival in patients with tumor. Such diagnosis requires not only high accuracy and flexibility but also clinical ...

Research Square 2026-04-21 rs-9434036
renal cell carcinoma circulating tumor cells blood cell counts prognosis inflammation-related indicator

Jun Yu, Jie Huang, Qinghua Ma, Yanyu Chen, Xinyue Huang, Jian Chen

Background: Sarcopenia represents a highly prevalent and prognostically detrimental complication in patients with bone tumors. Its progressive and dynamic nature hinders early intervention and amplifi...

BMC Musculoskeletal Disorders 2026-04-21 rs-9305260
Bone Neoplasms Sarcopenia Risk Assessment Predictive Model Nomogram Prognosis

Murat Uçar, Nureddin Raym, Uğur Soy, Erkan Karadağ, Murat Topçuoğlu, Ali Akkoç

Purpose To evaluate the prognostic value of preoperative hemoglobin-lymphocyte-neutrophil ratio (HLNR) and hemoglobin-lymphocyte-platelet ratio (HLPR) for predicting tumor recurrence at control cystos...

SN Comprehensive Clinical Medicine 2026-04-20 rs-9342974
Hematologic tests Prognosis Transitional Cell Carcinoma Urinary Bladder Neoplasms
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