1,010 results found

Mads Gyrd-Hansen, John Rizk, Frederik Timmermann, Wenxin Lyu, Kit Lee, Majken Kjær, Miriam Beichler, Berthe Fiil, Malin Jessen, Giulia Franciosa, Jesper Olsen, Max Sauerland, Rune Damgaard, Dominik Priesmann

Met1-linked ubiquitin (Met1-Ub) assembled by LUBAC crucially regulates immune receptor signalling. However, the regulation of LUBAC’s function remains widely debated. Here, we reveal that the interact...

Nature Portfolio 2026-04-22 rs-5519483
LUBAC PUB domain Met1-linked ubiquitin OTULIN CYLD SPATA2 TNF immune receptor inflammation cell death immunology

Taeyong Yun, Dawoon Jeong, Inho Hwang, Younghwa Ham, Pil Nam Seong, Jinhyeon Yun, Woongsup Lee

Tenderness is the most important factor affecting consumer satisfaction with beef. As demand for high-quality beef continues to grow, tenderness standards are receiving increased attention. Warner-Bra...

Scientific Reports 2026-04-22 rs-9262903

R. S. Ibrahim, M. W. Abbas, A. Nasiru

Background: Exogenous enzymes are increasingly used in ruminant nutrition to improve feed utilization and reduce nutrient losses. This study evaluated the the effects of different exogenous enzyme inc...

Research Square 2026-04-22 rs-8833196
Exogenous enzymes Kano Brown bucks feed intake nutrient digestibility blood profile manure production

Longcheng Luo, Xiaofan Zhang, Shun Yang, Qihang Huang, Kai Xiao, Cunfu Wang

The paper proposes a partition-based topology optimization approach for multi-axis additive manufacturing(AM), aiming to fully leverage its advantages in dynamic build orientation adjustment and regio...

Engineering with Computers 2026-04-22 rs-9018541
Multi-axis additive manufacturing Topology optimization Voronoi diagram based decomposition Overhang control Build orientation optimization

Riham Hilal, Mona G Ibrahim

AI technology development has transformed the field of engineering education with its adaptivity-driven, data-based, and ethical-led learning platforms that promote equity, diversity, and inclusivity....

Research Square 2026-04-22 rs-9458060
Artificial Intelligence (AI) Engineering Education Equality Diversity Inclusion (EDI) Ethical Leadership Human-Centered Learning Adaptive Pedagogy Digital Transformation Bias Mitigation Accessibility in STEM Sustainable Development Goals (SDGs); Gender Equality (SDG 5); Reduced Inequalities (SDG 10)

Shubham Kumar, Nihar Kumar Mahato, Md Abu T Ansary, Debdas Ghosh

Uncertain multiobjective optimization problems arise in various real-world scenarios where ob-jectives are affected by uncertainty. To address this, we propose a quasi-Newton method to solve the robus...

Soft Computing 2026-04-22 rs-9344639
Multiobjective optimization problem Uncertainty Robust optimization Robust efficiency Quasi Newton's method Line search techniques.

Xianlong Wei, Weilong Wu, Yang Li, Shuyu Mao, Fangyuan Zhan, Yuqiang Yu, Dan Su, Pan-Qin Sun, Bingjie Wang, Taoyuan Zhu, Ruixue Ding, Ye Zhao, Kechang Zhang, Tong Zhang, Zhiwei Li, Qing Chen

Higher resolution and higher throughput are the relentless pursuits of lithography technologies for continued downscaling of semiconductor devices 1. While the cutting-edge lithography technique for s...

Research Square 2026-04-22 rs-9432451

ABINAYASRI S

Purpose: By combining Role Identity Theory and Gender Role Theory, this paper explores the relationship between gendered role expectations and role satisfaction in mompreneurs. It seeks to know the in...

Research Square 2026-04-22 rs-9474255
Mompreneurship Gendered Role Expectations Role Identity Theory Role Conflict Role Enrichment

Zixing Xu, Zhechen Li, Xinhao Huang, Chuanrong Chen, Changyi Jiang, Weihong Xu

Spinal cord injury (SCI) often leads to significant neurological impairment and poses a substantial therapeutic challenge, with disulfidptosis recently identified as a potential mechanism exacerbating...

Molecular Neurobiology 2026-04-22 rs-9253233
Spinal cord injury Bisphenol A Disulfidptosis Metabolomics Key genes Key metabolites
Biological Sciences - Article under-review

Human physiology at the upper limit of extreme heat exposure

Ollie Jay, Jem Cheng, Jake McCahon, Lee Jin, Jennifer Vanos

Assessments of future human survivability under extreme heat with climate change have recently been anchored to a theoretical physiological tipping point: 6 hours of exposure to a wet-bulb temperature...

Nature Portfolio 2026-04-22 rs-9227989
physiological tipping point wet-bulb temperature extreme heat exposure human thermoregulation climate change impact
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