761 results found

Luca MAHARAVO, Stéphanie Ramboarina, Sofie Marijke Braet, Paul Corstjens, Danielle de Jong, Andriamira Randrianantoandro, Lovasoa Mbolamanana Joseph Andrianiriana, Mala Rakoto Andrianarivelo, Jean Luc Berland, Emmanuelle Cambau, Philip Supply, Agathe Jouet, Epco Hasker, Bouke Catherine de Jong, Bertrand Cauchoix, Tahinamandranto Rasamoelina, Luc Hervé Samison, Annemieke Geluk

Background: To curb the emergence of antibiotic-resistant Mycobacterium leprae strains, the WHO recommends monitoring of antimicrobial resistance (AMR). In Madagascar, molecular surveillance of resist...

Mycobacteria 2026-04-21 rs-9335540
Mycobacterium leprae Madagascar RLEP qPCR Drug resistance Genotype 1D-Malagasy anti-PGL-I serology

Fumihiko Furuya, Keiichi Nakano, Yoshiko Matsumoto, Koki Shio, Satoshi Suzuki, Satoru Suzuki, Hiroki Shimura, Hidetoshi Ando

Background: Accurate interpretation of thyroid ultrasound requires substantial experience, and diagnostic performance among trainees remains variable. Artificial intelligence (AI) has shown promise in...

BMC Medical Education 2026-04-21 rs-9329400

Ying Chao Peng, Rui Yin, Xin Rong Ye, Jiu Yu Liu, Chen Xi Ma, Yun Yun Lu, Jia Yi Shi, Chen bo Ji, Zheng Kun Xia, Chunlin Gao

Background Pediatric focal segmental glomerulosclerosis (FSGS) is a heterogeneous disease. Childhood is a dynamic developmental period, and age-related differences may influence disease presentation a...

Pediatric Nephrology 2026-04-21 rs-9280018
Focal segmental glomerulosclerosis Pediatric Disease trajectory Prognosis Age

Furkan Kozakoğlu, Merve Gürses

Objectives: This study aimed to evaluate the 1-year clinical performance of Ribbond-reinforced direct composite restorations placed in different orientations in endodontically treated posterior teeth....

Clinical Oral Investigations 2026-04-21 rs-9242123
Ribbond-reinforced composite endodontically treated posterior teeth modified USPHS different ribbond placement

Miguel Saro-Buendía, Manuel Mata, Alfonso García-Piñero, Lara Milián, Pedro Suárez-Urquiza, Miguel Armengot-Carceller

Transient receptor potential (TRP) channels are key regulators of nasal physiology and airflow perception, yet their longitudinal study is hindered by the invasiveness of conventional biopsies. This s...

Scientific Reports 2026-04-21 rs-8724816
Nasal mucosa Trigeminal nerve TRPV1 TRPM8 Biopsy Curettage Immunohistochemistry

Yi nan Gu, Zhitao Su

Background Open globe injuries with intraocular foreign bodies(IOFBs)are characterized by complexity and diversity.The removal of IOFBs poses a unique challenge to ophthalmic surgeons.Particularly for...

Research Square 2026-04-21 rs-9352609
Intraocular foreign body Open globe injury Slipknot Suture

Iman Farhadian Dehkordi, Kooroush Manochehri

This study introduces MAG, a lightweight intrusion detection system (IDS) that couples a single-hidden-layer multilayer perceptron (MLP) with the Adam optimizer and a Grey Wolf Optimizer (GWO) for hyp...

Research Square 2026-04-21 rs-9463244
Intrusion Detection Systems (IDS) Multilayer Perceptron (MLP) Grey Wolf Optimizer (GWO) Feature Selection KDDCup99 NSL-KDD

Pitithat Puranachot, Thivaratana Sinthuwiwat, Priyavudh Herabutya, Kanthida Jangyubol, Bongkod Petcharat, Jutamas Yimnoon, Jitsopin Phadungsut, Chayanee Samdaengpan, Chumut Phanthunane

Background: Accurately predicting treatment outcomes in patients with advanced non-small cell lung cancer (NSCLC) remains a significant clinical challenge. While circulating tumor DNA (ctDNA) within p...

BMC Personalized Medicine 2026-04-21 rs-9258115
Liquid biopsy monitoring Cell-free DNA Non-small cell lung cancer Progression-free survival Copy-number alterations cfDNA fragmentation Low-coverage whole-genome sequencing

Munesuishe Gotora, Ariana Mugore, Israel Sikumbili, Zainab Patel, Thom Kaledzera, Yohane Gadama, Reuben Kalavina, Nesto Tarimo

Background: Post-stroke depression is a common neuropsychiatric complication affecting stroke survivors worldwide, with a global prevalence of 20–50%. Establishing its prevalence and associated risk f...

Research Square 2026-04-21 rs-9287535
Depression Malawi Mental Health Stroke

Abdi Leta, Gamachu Diba

Background Oral administration is the preferred route for drug delivery due to convenience and patient compliance, yet its efficacy is hampered by low solubility and enzymatic degradation. Nanoparticu...

Research Square 2026-04-21 rs-9452361
nanoparticles oral bioavailability drug delivery systems pharmacokinetics
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