18 results found

Mian Muhammad Hamza, Ruhma Shahbaz

Background Esophageal abnormalities cause severe health complications. Diagnosis is traditionally performed on endoscopic imaging, but the method is highly subjective and prone to inter-observer varia...

Research Square 2026-04-21 rs-9399822
Esophagus Diseases Deep Learning Cohen’s Kappa score MCC SCORE Sea Shell SHAP Gradient-weighted Class Activation Mapping (Grad CAM) Integrated Gradients ResNet50V2

Hyunglok Kim, Hoang Nguyen, S.-Y. Simon Wang, Di Long, Venkataraman Lakshmi, Jin-Ho Yoon

Groundwater moves slowly, until it doesn't. Two decades of global satellite assimilated data reveal that aquifers in humid, energy-limited environments lose their storage at sub-seasonal timescales, t...

Nature Portfolio 2026-04-21 rs-9451212
flash drought groundwater soil moisture land-atmosphere ocean-atmosphere-land drought propagation teleconnection

Santiago Torres-Borda, Ahlem Mifdaoui

Among Time-Sensitive Networking (TSN) mechanisms, the Credit-Based Shaper (CBS) ensures bounded latency, while Frame Replication and Elimination for Reliability (FRER) enhances fault tolerance through...

Real-Time Systems 2026-04-21 rs-9314756
Time-Sensitive Networking (TSN) Credit-Based Shaper (CBS) Frame Replication and Elimination for Reliability (FRER) Network Calculus Optimization Schedulability

Gonçalo da Silva, Konstantin Barylyuk, Tasso Miliotis, Karin Jennbacken, Maria Ryaboshapkina

Endogenous cyanide has recently been identified in mammals and implicated in regulating mitochondrial function and the response to hypoxia. It is hypothesized to act as a gasotransmitter with function...

Research Square 2026-04-21 rs-9472761
Proteomics Cyanylation MASLD

Mel George, Leon Clarke, Jihoon Min, Shonali Pachauri, Anand Patwardhan, Narasimha D Rao, Haewon McJeon

Climate mitigation pathways impose uneven burdens across income groups, yet analyses typically focus on revenue recycling rather than on how pathway architecture shapes distributional outcomes. We exa...

Research Square 2026-04-21 rs-9442656
climate mitigation energy justice distributional impacts integrated assessment models demand-side mitigation effort-sharing

Susan Logue, Gideon Ong, Masozi Palata, Suraj Shaji, Joel Pearson

The Unfolded Protein Response (UPR) is a conserved network of signaling pathways controlled by the Endoplasmic Reticulum (ER) anchored stress sensors IRE1, PERK and ATF6. The UPR’s primary function is...

Cell Death & Disease 2026-04-21 rs-9373070
Endoplasmic Reticulum Stress Unfolded Protein Response ATF6 IRE1

Chunxia Zhao, Fang Fu, Tanghua Dai, Tian Zhan, Yan Wu, Xiaoqun Fang

Stroke, a leading cause of global mortality and disability, often results in post-stroke cognitive impairment, which significantly affects survivors and increases the risk of dementia. Loneliness and ...

Scientific Reports 2026-04-20 rs-7108707
Sroke mild cognitive impairment autonomous participation loneliness

Caíque de Oliveira Portugal Couto, Maria Luiza Hass das Eiras, João Lucas Juliao de Morais, Carlos Wagner Leal Cordeiro Júnior, Orestes Vicente Forlenza, VANESSA De Jesus Rodrigues de Paula

Alzheimer’s disease (AD) involves a progressive loss of neuronal integrity in which chronic neuroinflammation is increasingly recognized as a contributing factor. Sustained activation of innate immune...

Molecular Neurobiology 2026-04-20 rs-9077098
Phosphatidylinositol-3-kinase Alzheimer's disease Lithium Ontological pathways Neuroplasticity
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