998 results found

Pitithat Puranachot, Thivaratana Sinthuwiwat, Priyavudh Herabutya, Kanthida Jangyubol, Bongkod Petcharat, Jutamas Yimnoon, Jitsopin Phadungsut, Chayanee Samdaengpan, Chumut Phanthunane

Background: Accurately predicting treatment outcomes in patients with advanced non-small cell lung cancer (NSCLC) remains a significant clinical challenge. While circulating tumor DNA (ctDNA) within p...

BMC Personalized Medicine 2026-04-21 rs-9258115
Liquid biopsy monitoring Cell-free DNA Non-small cell lung cancer Progression-free survival Copy-number alterations cfDNA fragmentation Low-coverage whole-genome sequencing

Abhijit Dutta, Dewan Md. Sumsuzzman, Daniel Wrzałko, Robbert van Haselen, Petra Weiermayer, Katharina Gaertner, J.A.D.S. Lakshani, Sabine Klein, Stephan Baumgartner, Martin Loef

Background: Insomnia is a prevalent disorder associated with substantial impairment. Homeopathy has been proposed as a complementary treatment for insomnia, but its clinical effects remain uncertain. ...

Research Square 2026-04-21 rs-9439398
Insomnia Homeopathy Systematic Review Meta-analysis Sleep disorders Funding: Software AG Stiftung Darmstadt Germany

Munesuishe Gotora, Ariana Mugore, Israel Sikumbili, Zainab Patel, Thom Kaledzera, Yohane Gadama, Reuben Kalavina, Nesto Tarimo

Background: Post-stroke depression is a common neuropsychiatric complication affecting stroke survivors worldwide, with a global prevalence of 20–50%. Establishing its prevalence and associated risk f...

Research Square 2026-04-21 rs-9287535
Depression Malawi Mental Health Stroke

Abdi Leta, Gamachu Diba

Background Oral administration is the preferred route for drug delivery due to convenience and patient compliance, yet its efficacy is hampered by low solubility and enzymatic degradation. Nanoparticu...

Research Square 2026-04-21 rs-9452361
nanoparticles oral bioavailability drug delivery systems pharmacokinetics

Shukhrat Djabbarov, Abdusaid Yuldashov, Bakhrom Abdullaev, Irina Soboleva, Шерзод Файзибаев, Nargiza Yuldashova, Nassim Rustamov

The safe operation of heavy freight trains on steep mountain railway sections depends on effective control of longitudinal in-train forces during start-up and traction transitions. This study investig...

Scientific Reports 2026-04-21 rs-9364175
longitudinal train dynamics coupler force freight train steep gradient field validation MSC Adams

Aisha Ghazanfar, Saba Zaidi, Shafiq Ur Rehman, Hazim Brohi

Introduction: Pulmonary arteriovenous malformations (PAVMs) are abnormal vascular connections that predispose to paradoxical embolism and brain abscess formation. They often remain undetected until se...

Research Square 2026-04-21 rs-9335231
Hereditary Hemorrhagic Telangiectasia Brain abscess Pulmonary Arteriovenous Malformation paradoxical embolism

Tien Nguyen

Background Metabolic syndrome (MetS) is common in older adults and is associated with cardiovascular disease, type 2 diabetes, and functional decline. In Vietnam, evidence on MetS in older adults is s...

BMC Geriatrics 2026-04-21 rs-9399614
metabolic syndrome older adults elderly prevalence Vietnam systematic review meta-analysis

Kamna Redhu, Ajay Kumar, Jagdish Parshad, Meena Sindhu, Ravinder Kumar, Sushil Nagar, Suruchi Sangwan, Monika Jangra, Rajbala Yadav

Metal-based nanoparticles are known for their ecotoxicological and phytotoxic effects, impairing plant growth and development. However, several nanoparticles, including those of zinc, are essential fo...

Discover Agriculture 2026-04-21 rs-9231087
Zinc oxide nanoparticles Biofertilizer Rhizobium Characterization Mungbean

James F. White, Walter A. Goldstein, Colin Treiber, Clara Zinky, Julian Mayfield

Rhizophagy provides wild plant species with nutrients through bacterial assimilation.  We evaluated inbreds which had been developed under nutrient-limited, biodynamic-organic farming conditions by th...

Research Square 2026-04-21 rs-9131646
endophyte colonization trichomes root cap cells mucilage root health rhizophagy

Minxin He, Haibin Zhou, Xiangyu Wang, Mingrui Li, Tie Chong

Purpose: Early diagnosis of tumor recurrence or metastasis is critical for prolonging survival in patients with tumor. Such diagnosis requires not only high accuracy and flexibility but also clinical ...

Research Square 2026-04-21 rs-9434036
renal cell carcinoma circulating tumor cells blood cell counts prognosis inflammation-related indicator
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